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Toxicology Laboratory at the Veterans Administration, Portland, Oregon, USA, Agilent Technologies

Wyatt Technology Corporation

Bruker Daltonics

Click the title above to open the LCGC Europe September 2013 Applications Book, Vol 26 No s9, in an interactive PDF format.

The 40th International Symposium on High Performance Liquid Chromatography and Related Techniques (HPLC2013-Hobart) will take place at the Hotel Grand Chancellor, Hobart, Tasmania, Australia, from 18–21 November 2013.

A review of the trends at this year's symposium, including discussions of column technology, sample preparation, and detector usage.

How do you identify the cause of unstable retention times?

In this instalment, a way of utilizing HR-MS systems to characterize the structures of metabolites is introduced. This results in a general workflow for metabolism studies for drug discovery and development.

Secrets to Successfully Translating and Transferring HPLC Methods

UCT Application Note

In this instalment, John Hinshaw compares the GC separation process to a long-distance run through a long corridor with some unique properties. The runners are separated in various ways.

The American Chemical Society (ACS) has named Daniel W. Armstrong, professor of chemistry and biochemistry at the University of Texas (UT) Arlington, to its 2013 Class of Fellows.

Wyatt Technology Application Note

The reasons that make HPLC so ubiquitous; the fundamentals on how we conduct HPLC separations; and a few opportunities with far-reaching impacts in life sciences for separation scientists are discussed in this article.

Understanding the chemistry behind gas chromatography (GC) separations can lead to faster problem identification and improved troubleshooting.

In contrast to isocratic separations, gradient elution can sometimes seem to be counter-intuitive. Yet with the proper perspective, the things we intuitively understand about isocratic methods apply in a similar manner to gradients.

Material identification is a common need in many industries, most notably for pharmaceutical manufacturing where the United States Pharmacopeial Convention (USP) defines many identification tests.

This article describes the GC–MS and LC–MS screening methods developed for the analysis of both low-volume water samples and extracts obtained from various designs of passive samplers.

Click the title above to open the LCGC Asia Pacific September 2013 regular issue, Vol 16, No 3, in an interactive PDF format.

Click the title above to open the LCGC Europe September 2013 regular issue, Vol 26 No 9, in an interactive PDF format.

Click the title above to open the LCGC North America September 2013 Application Notebook, Vol 31 No s9, in an interactive PDF format.

Click the title above to open the LCGC North America September 2013 regular issue, Vol 31 No 9, in an interactive PDF format.

Click here to view the full European E-newsletter from 29 August.

Experts in the food industry are always searching for natural sources of bioactive compounds to develop products that enhance athletic performance. A new study has suggested that drinking watermelon juice may alleviate muscle ache experienced by many athletes, and non-athletes, following a period of exercise. The study published in the Journal of Agricultural and Food Chemistry showed that naturally high levels of L-citrulline in watermelon juice may be more effective than pharmacological supplements.

Part 1 of evidence to demystify HPLC and UHPLC column myths

Scientists from the University of Bradford (Bradford, UK) have utilized liquid chromatography?tandem mass spectrometry (LC-MS-MS) to gain further insight into the child sacrifice practices of the Inca people.1 Their findings indicate the use of alcohol and cocaine (COC) as a method of victim sedation.