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An excerpt from LCGC's e-learning tutorial on quadrupole mass analysers at CHROMacademy.com

In the 1960s, high performance liquid chromatography (HPLC) was in its infancy and Phyllis Brown was a pioneer at the forefront of the technique.

HPLC 2013

Click the title above to open the LCGC Asia Pacific November 2012 regular issue, Vol 15, No 4, in an interactive PDF format.

Click the title above to open the LCGC North America November 2012 regular issue, Vol 30 No 11, in an interactive PDF format.

The HPLC 2012 conference was abuzz with talk of "slip flow" following the talk given by Mary Wirth of Purdue University about her groundbreaking work involving protein column efficiency. In this interview, Wirth explains how “slip flow†works and what this discovery can contribute to the application of LC-MS to disease research.

The HPLC 2012 conference was abuzz with talk of "slip flow" following the talk given by Mary Wirth of Purdue University about her groundbreaking work involving protein column efficiency. In this interview, Wirth explains how “slip flow†works and what this discovery can contribute to the application of LC-MS to disease research.

The University of Texas at Arlington (UT) (Texas, USA) has announced its investment of $7.5 million into the creation of the Institute for Research Technologies at UT Arlington, adding to the philanthropic investment made by Shimadzu (Duisburg, Germany) earlier this year.

Thermo Fisher Scientific (California, USA) has collaborated with Immunodiagnostik (Bensheim, Germany) to develop novel assays for the commercial qualitative and quantitative analysis of protein and peptide biomarkers in disease diagnosis

High-pressure capillary ion chromatography systems enable use of 4 µm particle-size columns for high-efficiency separations. Choose your optimum balance between fast analysis and high resolution.

The University of Texas at Arlington (UT) (Texas, USA) has announced its investment of $7.5 million into the creation of the Institute for Research Technologies at UT Arlington, adding to the philanthropic investment made by Shimadzu (Duisburg, Germany) earlier this year.

Merck Millipore is the Life Science division of Merck KGaA of Germany and offers a broad range of innovative, performance products, services and business relationships that enable our customers? success in research, development and production of biotech and pharmaceutical drug therapies.

Introducing the flexible Contichrom® lab process equipment

Petrochemical Profiling

Essential oil inhalation is a holistic and economic treatment for the alleviation of anxiety. Whether this effect is of a psychological or physiological basis has been in dispute since the beginnings of ‘modern’ medicine. Many would argue that any effects felt are simply psychological, a ‘placebo’ effect, as if the individual believes the treatment will aid them it does.

Urinary excretion profiling is a key element in the pharmokinetic characterization of new chemical entities (NCEs). Recent advances in ultra-high performance liquid chromatography (UHPLC) column technology offer improved results for liquid chromatography tandem mass spectrometry (LC–MS¬–MS) analysis, enabling rapid quantification of specific drugs and their metabolites in biological matrices.

The Column spoke to Hans van den Heuvel, the Product Marketing Manager for Bruker Chemical & Applied Markets.

Malaria is the 5th responsible cause of death from infectious disease worldwide, and approximately half the global population are at risk. 1A team of scientists in Missouri, USA3 has recently answered a long-standing question regarding the metabolism of the parasite, advancing research towards identifying novel therapeutics

Drug bioavailability, the rate at which the active compound of a drug becomes available at the site of action, is key to the successful development of new drugs. The development of hydrogels, self-assembling polymer-based scaffolds, has rapidly accelerated in recent years because of their potential in the improvement of drug bioavailability.

Organophosphates (OPs) are commonly found in commercial pesticides and are highly toxic to humans if inhaled or ingested, resulting in both behavioural and psychological symptoms. OPs chemically modify the essential protein acetylcholine esterase, which is principally responsible for the breakdown of the essential neurotransmitter acetylcholine.

Incognito ruminates on the value of setting up a method from scratch.

In der Oktober-Ausgabe von LCGC Ausgabe in deutscher Sprache beschäftigen wir uns mit zertifizierten Referenzmaterialien und der Bedeutung von ISO Guide 34, sowohl für die Hersteller als auch für die Endverbraucher. Der regelmäßige Kolumnist von „GC-Verknüpfungen“, John V. Hinshaw, ergänzt seine Serie von Juni 2011 um eine weitere Folge und erörtert den Einsatz von Gasschaltventilen zur Säulen-Rückspülung und für zweidimensionale Serien-Bypass-Anwendungen.

Waters EU - Chiesi and Waters Implement a Lean, Paperless Lab

Karyn M. Usher of West Chester University of Pennsylvania interviews Phyllis R. Brown, professor emerita of the University of Rhode Island, about her distinguished career in chromatography.

Themro EU - Rapid Determination of Persistent Organic Pollutants (POPs) Using Accelerated Solvent Extraction

Themro EU - Rapid Determination of Fat in Meat Using Accelerated Solvent Extraction

Themro EU - Extraction of Total Petroleum Hydrocarbon Contaminants (Diesel and Waste Oil) in Soils by Accelerated Solvent Extraction

Themro EU - Extraction and Cleanup of Acrylamide in Complex Matrices Using Accelerated Solvent Extraction Followed by Liquid Chromatography Tandem Mass Spectrometry (LC–MS-MS)