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The majority of the human brain is not yet fully understood and we still have a lot to learn about its workings. A group of scientists have performed a comprehensive first characterization of the human occipital lobe (primary visual cortex) and cerebellum proteomes from 12 post-mortem samples.

Recent Developments in LC Column Technology.

Trace-Level GC-MS Analysis of Pesticides

A review of a gas chromatographic procedure developed for the direct measurement of trace levels of lindane, aldrin, heptachlor epoxide, dieldrin, o,p-DDD, and dichlorodiphenyltrichloroethane (DDT)

A look at the process of forming radical cations for analysis in GC–MS and the role of various ion source components

The use of dynamic coating systems/approaches in CE can result in improved routine performance and/or selectivity.

A review of columns unveiled at Pittcon this year, including all modes of HPLC, UHPLC, and liquid-phase separations.

Mistakes or fat finger moments are part of human nature but where is the dividing line between this and falsification and fraud?

Highlights of some of the new HPLC and related technology showcased both before and at this year's conference

Event news summary

The use of in vivo SPME offers important advantages over conventional methods according to the authors, including simplified sample clean-up, fast stabilization of unstable analytes, elimination of enzymatic degradation after extraction and reduced ion suppression for mass spectrometry analyses.

A brief review of the physicochemical properties of core–shell particles and their chromatographic efficiencies compared with those of sub-2-µm fully porous particles

A discussion of new column packing materials - including sub-2-µm particles, superficially porous particles, and second-generation monoliths - and their impact on instrumentation and laboratory productivity

The fundamentals of size-exclusion chromatography, packing properties, and practical approaches for increasing resolution

Click the title above to open the LCGC North America April 2012 regular issue, Vol 30 No 4, in an interactive PDF format.

Click the title above to open the LCGC North America April 2012 Recent Developments in LC Column Technology, Vol 30 No s4, in an interactive PDF format.

From sample prep to low detection levels to automation, environmental analysis provides unique challenges for analytical chemists. Participants in this Technology Forum are Kory Kelly of Phenomenex (Torrance, California) and LCGC Editorial Advisory Board member Pat Sandra of the Research Institute of Chromatography (Kortrijk, Belgium).

Hichrom Limited are pleased to announce the acquisition of the Partisil® and Partisphere® HPLC column consumable product line from Whatman, a division of GE Healthcare. Based in the UK, Hichrom are a leading European manufacturer and distributor of HPLC columns, consumables and media, with manufacturing facilities accredited to both ISO9001 (Quality) and ISO14001 (Environmental) standards.

Hichrom Limited are pleased to announce the acquisition of the Partisil® and Partisphere® HPLC column consumable product line from Whatman, a division of GE Healthcare. Based in the UK, Hichrom are a leading European manufacturer and distributor of HPLC columns, consumables and media, with manufacturing facilities accredited to both ISO9001 (Quality) and ISO14001 (Environmental) standards.

Agilent (Santa Clara, California, USA) has announced that it has entered into a Cooperative Research and Development Agreement with the US Food and Drug Administration (FDA) to develop new tools to detect and analyse pathogens in food.

Sigma-Aldrich (St. Louis, Missouri, USA) has announced that they have opened a new facility in Wuxi, China that will provide localized packaging, analytical services and quality control to support the company?s research and customers in the region.

Waters (Milford, Massachusetts, USA) has announced that it has formed a partnership with the Irish National Institute for Bioprocessing Research and Training (NIBRT) to address the world?s most challenging diseases through training and research.

AB SCIEX (Framingham, Massachusetts, USA) has opened a new Asia Pacific Application and Training Centre in Singapore?s biomedical hub at Biopolis.

Global Water Instrumentation (GWI) (Sacramento, California), a division of Xylem (White Plains, New York), has teamed up with the Alabama Cooperative Extension Service (Auburn, Alabama), the Auburn University School of Architecture, Planning, and Landscape Architecture (Auburn, Alabama), and the Auburn University Department of Biosystems Engineering to study hydraulic, hydrologic, and water quality changes during the transition of forested land to a residential "low impact development" (LID) subdivision.

The consumption of beer is, for some, one of life?s great pleasures but it can leave behind a bitter aftertaste

A new method has been developed for the identification and classification of various tuberculosis (TB) causing and non-TB Mycobacterium species on the basis of their characteristic metabolite profiles.

Water EU - Determination of Soy Isoflavones in Foods and Dietary Supplements by UPLC

Spectrum Chemicals and Laboratory Products has announced that they have signed a distribution agreement with PerkinElmer.