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Agilent Technologies and Oxford Gene Technology have announced that they have expanded an already existing partnership into an exclusive agreement for Agilent to provide OGT with oligonucleotide microarrays

Automating the DNA sequence process is made possible by the use of fluorescent tags. With fluorescent dyes, the entire experiment can be performed in a single solution instead of four different ones. Using Sanger-based methods, the DNA fragments migrate through the gel and the colour associated with each successive peak is detected using a laser. The DNA sequence is read by determining the sequence of colours in the peaks as they pass the detector and then fed directly to a computer for instant results.

The separation of intact glycoproteins presents a great challenge because one glycoprotein can exhibit many isoforms with close physiochemical properties. As a result, it is difficult to study them in isolation. A team of chemists from Nanjing University, China, have tested a polymeric weak anion exchange (WAX) monolithic capillary to assess the high resolution separation of glycoprotein isoforms, to see whether this provides the desired results.

A team of researchers led by Nawed Deshmukh of the School of Pharmacy and Chemistry at Kingston University (London, UK) has published new research using liquid chromatography?tandem mass spectrometry (LC?MS?MS) to identify steroid contamination in environmental water samples in Budapest, Hungary.

Scientists Zhi-Min Long, Kai-Shun Bi, Yan-Shuang Huo, Xiao-Yu Yan, Xu Zhao and Xiao-Hui Chen at Shenyang Pharmaceutical University, (Shenyang, China) developed and validated a sensitive and efficient liquid chromatography?mass spectrometry (LC?MS) method for the simultaneous determination of geniposide 6?-hydroxygeniposide and genipin gentiobioside in rat plasma.

Janet Kelsey spoke to Jean Bléhaut, Director, Marketing & Business Development at Novasep about the general trend in on-line process analysis, its most common applications and how demand for preparative chromatography has grown over the past few years.

Waters NA - Dramatically Enhanced Sensitivity with StepWave Ion Transfer Technology

We have nothing to declare but our Genius.

Agilent has announced the winners of their 2011 eMerging Insights grant programme, each of whom will receive $75,000 towards their ongoing research on open source data-integration tools.

Click here to view the complete E-Separation Solutions newsletter from November 3, 2011, 2011.

Click here to view the complete E-Separation Solutions newsletter from November 3, 2011, 2011.

Scientists at the University of Granada (UGR) (Granada, Spain) have identified and characterized different antioxidant compounds from foods such as olive oil, honey, walnuts, and the medicinal herb, Teucrium polium.

Bruker - Definite Answers for Structure Elucidation inMetabolomics Research

amaZon speed – accelerating access to proteomicinformation

The 26th International Forum and Exhibition Process Analytical Technology (Process Analysis and Control) (IFPAC) conference will be held at the Baltimore Marriott Waterfront (Baltimore, Maryland) on January 22-25, 2012.

A simple experimental setup applied in a drug discovery laboratory illustrates some anomalies and misconceptions about supercritical fluid chromatography for drug discovery.

An interview with John Knox, who brought us the Knox equation, porous graphite carbon, and other critical advances in both liquid and gas chromatography.

Combining a membrane with a solid sorbent can improve selectivity and save time in sample preparation.

This month the use of fluidic switching devices for open-tubular column manipulations is discussed.

Event news summary

PSS Application Note

Thermo Scientific Application Note

Waters Application Note

Waters Application Note

A review of some of the advances in technology and new applications presented at HPLC 2011, held in Budapest, Hungary.

Metrohm Application Note

Demonstrates how lo-abundant clomazone metabolites buried under dominating abundant metabolites can be successfully detected, analysed and characterised.

Waters Application Note