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Protein/peptide discovery data obtained from data-dependent experiments have been used to increase the success rate of targeted quantification assays as well as automate method building.

Global warming is a contentious issue, with different groups voicing opposing opinions on if, how and at what rate the warming is occurring. The general consensus is that with increased industrialization, greenhouse gas emissions have also increased, resulting in the formation of a so-called 'greenhouse effect'. The origin of greenhouse gases is therefore of great interest to the scientific community.

GPC/SEC (gel permeation chromatography/size exclusion chromatography) methods generally contain multiple detectors in order to gather more information about the molecular structure of macromolecules.1. Up until now, however, the practice and the impact of detector combination has not been discussed.

Spodoptera littoralis is a destructive caterpillar pest indigenous to tropical and subtropical areas of agriculture that has the potential, if accidentally imported, of becoming a major greenhouse pest in Northern Europe. The UK government agency Defra reports that many populations of the species are already highly pesticide resistant2.

The Column spoke to Dr J-F Focant, associate professor at the chemistry department of the University of Liege, Belgium, about thenatochemistry and his recently published articles profiling the 'smell of death'.

Conditions of acute and chronic anaemia that are the result of either a long-standing medical condition (sickle-cell anaemia) or surgical intervention (chemotherapy) often require the administration of blood transfusions to improve the capacity of the patient's red blood cells to carry oxygen1. Red blood cell (RBC) populations have a short shelf life in storage as a result of biomechanical and biochemical changes that reduce the RBC functionality. This has an impact on the viability and therapeutic benefits of ex vivo RBC transfusions.

Preparing Red Wine Extracts for LC-MS-MS Pesticide Analysis

The authors characterized twelve SFC achiral stationary phases with 60 compounds from four chemical classes to establish guidelines for the rational selection of the optimum stationary phase for separations.

In this month's installment, John Hinshaw discuses solid-phase micro extraction.

An update on some of the latest chiral stationary phases and their use in various separation modes.

Lab Innovations 2012

The solvent chosen for injection can affect the appearance of chromatographic peaks.

A brief review of the physicochmical properties of core-shell particles and their chromatographic efficiencies compared with those of sub-2-?m fully porous particles.

An excerpt from LCGC's e-learning tutorial on preparative HPLC at CHROMacademy.com

Click the title above to open the LCGC North America October 2012 regular issue, Vol 30 No 10, in an interactive PDF format.

Click the title above to open the October 2012 issue of Current Trends in Mass Spectrometry, Volume 10, Number 4, in an interactive PDF format.

With further improvements in instrumentation and column design, supercritical fluid chromatography (SFC) Is becoming a mainstream technology.

AB SCIEX (Massachusetts, USA) and the University of Wollongong (UOW) (Wollongong, Australia) have formed a partnership to advance research in lipid analysis, as part of AB SCIEX’s academic partnership programme.

Thermo Scientific SOLA products revolutionize Solid Phase Extraction (SPE). This first fritless SPE product range provides greater reproducibility with cleaner, more consistent extracts.

With further improvements in instrumentation and column design, supercritical fluid chromatography (SFC) Is becoming a mainstream technology.

AB SCIEX (Massachusetts, USA) and the University of Wollongong (UOW) (Wollongong, Australia) have formed a partnership to advance research in lipid analysis, as part of AB SCIEX’s academic partnership programme.

Markes International (Llantrisant, UK) has announced the formation of a partnership with Cardiff University (Wales, UK) and twelve partner organisations from across Europe to undertake a research project aimed at the improvement of the safety and quality of pre-packed fruit and vegetables. The initiative is co-funded by the European Commission through the 7thFramework program.

Agilent has announced the opening of a new customer applications and training centre in South Korea.

Agilent (California, USA) has formed a co-marketing agreement with Molecular Discovery Ltd (Perugia, Italy).

LCGC recently spoke with Fred E. Regnier, the John H. Law distinguished professor in the Department of Chemistry at Purdue University (West Lafayette, Indiana, USA) and a member of LCGC's editorial advisory board.

Phenomenex (Torrance, California, USA) has announced the creation of a new company Phenova, Inc. ; the culmination of the integration and expansion of Colorado-based Wibby Environmental.

Click here to view the complete E-Separation Solutions newsletter from September 20, 2012.

At the International Mass Spectrometry Conference (IMSC) in Japan, AB Sciex (Massachusetts, USA) announced the introduction of an initiative targeted at the development of biologics, a rapidly growing research area within the field of drug discovery.