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A fast, selective, and reproducible high performance liquid chromatography (HPLC) method was developed and validated for the analyses of third-generation cephalosporin antibiotics, namely, ceftriaxone, cefixime, and cefdinir in human plasma. The analysis was carried out on a 150 mm Ã- 4.6 mm, 5.0-µm C18 column. The mobile phase used was 80:20 (v/v) 50 mmM phosphate buffer (pH 5.0)–methanol at a flow rate of 1.0 mL/min with 230-nm UV detection.

Largest ever catalogue

Agilent Technologies' 2011-2012 Essential Chromatography and Spectroscopy Catalogue has been published and with the company?s acquisition of Varian, is 50% larger than the previous edition.

Bruker is set to acquire Michrom Bioresources, a Californian company that provides LC instrumentation, accessories and consumables for applications in the life science, chemical and applied markets.

2011 Emerging Leader

Click here to view the complete e-Separation Solutions newsletter from March 28, 2011.

Cytotoxic leaves

A chromatographic study of extracts from the leaves of a Calomeria amaranthoides has found potent anti-cancer effects against ovarian cancer cells.

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LCGC's Editorial Director, Laura Bush, presented Dwight R. Stoll, Assistant Professor in the Department of Chemistry at Gustavus Adolphus College, with the 2011 LCGC Emerging Leader award at Pittcon this year. Afterward, she invited him to talk about his career and work.

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D-ficient

As many as 70% of Americans may not be getting enough vitamin D but the average American does eat three slices of bread a day. A recent study has suggested that bread made from vitamin D-rich yeast could be used to bridge the gap.

German companies instrAction and Protagen have signed a strategic alliance for the development of customized phases for downstream processing of biotherapeutics.

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In 2001 and 2005 two research vessels detected unexpectedly high air concentrations of polychlorinated biphenyls (PCBs) off the coast of West Africa. To investigate this further a study has been conducted on air samples from all over the West African coast.

Dal Nogare award

The 2011 Dal Nogare award has been presented to Janusz Pawliszyn at Pittcon 2011.

Applicable for the determination of naphthalene, fluorene, phenanthrene, anthracene, fluoranthene, pyrene, benz[a]anthracene, chrysene, benzo[a]pyrene in seafood tissues including finfish and shellfish. The method is expected to be applicable to alkylated PAHs and related compounds in similar matrices. Limits of quantitation were shown to be < 1ng/g.