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Signal-to-noise of a chromatographic peak from a single measurement has been used determine the performance of two different MS systems, but this parameter can no longer be universally applied and often fails to provide meaningful estimates of the instrument detection limits (IDL).

The impact of speed of analysis and selectivity to the depth of coverage and accuracy of the analyses are discussed.

A single calibration curve run with staggered calibrants bracketing the unknowns is compared to running complete duplicate calibration curves, one at the beginning and one at the end of unknown sample analysis in an effort to accelerate discovery bioanalysis.

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A newly developed high-throughput method for the quantitation of vitamin D using both multiplexed LC and on-line SPE is discussed.

Click the title above to open the LCGC North America May 2011 regular issue, Vol 29 No 5, in an interactive PDF format.

Click the title above to open the May 2011 issue of Current Trends in Mass Spectrometry, Volume 9, Number 2, in an interactive PDF format.

Flavour analysis of a Bloody Mary has provided some key insights into the best ways to mix the drink. The challenges and findings of cocktail?s analysis were presented at the 241st National Meeting & Exposition of the American Chemical Society.

Investigating a more effective alternative to current hepatitis C treatment therapy, scientists have studied the effects of Silybum marianum (milk thistle) seeds on the hepatitis C virus (HCV) 3a core gene.

Actinomycetes in soil produce various antifungal compounds that may protect crops from anthracnose disease.

Scientists have used stepwise weak anion exchange (WAX) chromatography to fractionate the urine proteome and to enrich low-abundance proteins that are often obscured by high-abundance proteins.

The analytical spectrometry research group at the University of Oviedo in Asturias, Spain has implemented the Thermo Scientific XSERIES 2 ICP-MS to perform interference-free sulphur detection in proteins.

Bruker completes acquisition of Michrom and moves Chemical & Applied Markets division to Fremont, California.

Click here to view the complete e-Separation Solutions newsletter from April 21, 2011.

Joining us for a discussion on hyphenated techniques are Ian Jardine from Thermo Fisher Scientific, Massimo Santoro from PerkinElmer and Jürgen Wendt from Leco.

The European patent office has granted a patent entitled ?Proteome-wide quantification of small molecule binding to cellular target proteins? to German company, KINAXO Biotechnologies.

NASA has selected ITT Analytics' OI Analytical total organic carbon analyser to measure water quality on board the International Space Station. A conductivity temperature meter from the company will also be used.

What are the latest trends in hyphenated techniques and what benefits do they offer? We asked Ian Jardine, Thermo Fisher Scientific; Massimo Santoro, Perkin Elmer; and Jürgen Wendt, Leco.

The three main types of volatile extraction techniques are purge & trap, headspace, and thermal desorption equipment.

Dionex NA - Measurement of siRNA Cell-Penetrating Peptides

Dionex NA - siRNA Transfection Agents by Charged Aerosol Detection

We discuss polyolefins and high temperature GPC in terms of engineering advances.

Thermo Fisher Scientific has completed the previously announced sales of its two laboratory-testing services businesses, Athena Diagnostics and Lancaster Laboratories, in two separate transactions, resulting in total proceeds of $940 million.

Dionex NA - Trace Nickel and Zinc in Power Plant Waters

Dionex NA - Enrichment and Identification of Chicken Ovalbumin Phosphopeptides

Dionex EU - Enrichment and Identification of Chicken Ovalbumin Phosphopeptides

Dionex EU - Trace Nickel and Zinc in Power Plant Waters

Tosoh Product Profile