All News

LECO?s patented ChromaTOF software provides a one-stop software package for a fully automated instrument solution from sample introduction, data acquisition, True Signal Deconvolution (TSD) to analyte quantification and report generation.

Monoclonal Antibody Heterogeneity by Cation-Exchange Chromatography - Dionex Apps Notes

Agilent Technologies, Inc. (Santa Clara, California) announced its collaboration with software product development company Persistent Systems (San Jose, California) to promote multivendor chromatography system interoperability.

Eluent Consumption by Optimizing UltiMate 3000 Quaternary Analytical Systems for Small Column Volumes - Dionix Apps Note

Organic Acid Analysis: Simple, Easy & Reliable - Microsolv Apps Note

SGE Analytical Science has appointed Ian Ransley, PhD, as director of the mass spectrometry business unit.

MALS for Proteins - Wyatt Apps Note

There is an old saying regarding the world of fashion that says if you wait long enough, everything comes back into style eventually.

Waters Application Note

PerkinElmer Application Note

Waters Application Note

Describing the theoretical background on how the separations occur, the operating approaches that can be taken and method development.

Euroanalysis 2009, which is organized under the umbrella of the Division of Analytical Chemistry (DAC) of the European Association for Chemical and Molecular Sciences (EuCheMS), has become a premier event for scientists to discuss and hear presentations on a broad spectrum of analytical techniques from a diverse range of applications. Euroanalysis aims to bring together analytical chemists from various fields to stimulate communication and strengthen networks in analytical sciences.

When is curve weighting a good idea?

Chiral Technologies, Inc. (West Chester, Pennsylvania), a global provider of chiral chromatography columns, has signed a distribution agreement with Canadian Life Science (Peterborough, Ontario) to better serve its customers throughout Canada.

A multilaboratory collaborative study organized by the Human Proteome Organization demonstrated that participating laboratories had difficulty in identifying components of a simple protein mixture.

Tips & Tricks: GPC/SEC

LCGC Europe has revamped its digital media portfolio to complement the peer-reviewed magazine.

Planar chromatography e-book; Web-based dashboard; On-demand webinars; Streamline syringe selection; Chromatography software update

Short Courses

Calendar

There is an old saying regarding the world of fashion that says if you wait long enough, everything comes back into style eventually. While this saying may have provided the necessary excuse for many people (myself included) to avoid throwing away favorite old articles of clothing, the underlying truth that everything is cyclical cannot be denied, and this certainly holds just as true for the field of chromatography as it does for any other field.

In a market as dynamic and fast-paced as ours, it should come as no surprise that in the months since I last addressed our readers in this space, a great deal has taken place in the world at large and in the field of separation science in particular.

The introduction of the new Kinetex™ core-shell technology provides a significant benefit to all separation scientists looking to increase sample throughput by reducing chromatographic analysis times while maintaining chromatographic resolution.

Supercritical fluid chromatography (SFC) has been practiced for approximately 50 years. SFC on packed columns for both qualitative and quantitative purposes underwent a renaissance in interest at the beginning of the 1990s when limitations of capillary SFC became obvious and important progress in composition gradient techniques for mixed mobile phases was achieved. Even with these instrumental improvements, wide acceptance of the technology was not forthcoming because the perception was that highly polar analytes were not soluble in carbon dioxide and thus were not separable. It is now apparent that the use of additives dramatically extends the range of solute polarity amenable to SFC.

The high-throughput analysis of pesticides in raw agricultural commodities has been hindered by the slow and laborious sample preparation stages. Using traditional clean-up procedures, as many as 20 steps are required to get the sample in a convenient form for analysis, which typically limits sample throughput to eight samples per day. This study evaluates a new approach using a novel laboratory mill and pulverizer to extract various pesticide residues from different kinds of plant materials and to identify and quantitate the active ingredients by liquid chromatography–tandem mass spectrometry (LC–MS-MS). It shows that by automating the procedure, the number of clean-up steps can be reduced significantly, which increases sample throughput over traditional approaches.

The answer to the following reader question about protein separations was supplied by LCGC's "Directions in Discovery" columnist Tim Wehr.

Varian, Inc. has published an application note entitled Determination of Aminoglycoside Antibiotics by HPLC with ELSD. Streptomycin and neomycin are members of the family of antibiotics called aminoglycosides.