
The use of a silica column for HILIC is examined, including mechanistic studies of analyte retention on silica in aqueous-organic mobile phases.

The use of a silica column for HILIC is examined, including mechanistic studies of analyte retention on silica in aqueous-organic mobile phases.





This month'ss guest authors review the application of solid-phase SPME to the analysis of drugs in human plasma.

This month's "GC Connections" examines the various ways – and their attendant benefits and drawbacks – with which chromatographers and chromatography data-handling systems locate and measure peaks

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An overview of some recently developed mass spectrometry techniques and their applications to marine biotoxins.




The author describes the development of a method for the extraction, clean-up, and successful analysis of polybrominated diphenyl ethers (PBDEs) in fish tissue, soil, and water.

In the first instalment of this new column, Massart and Vander Heyden review the subject of chemometrics, and in particular its relevance to separation science. The column aims to explain how application of chemometrical techniques can improve both the design of robust analytical methods and the subsequent interpretation of derived results.

The authors look at how achieving both greater throughput and increasing informational content is a driving force in small-molecule analysis. They describe how analysts should address mechanical increases in productivity, software implementation flow and data management, and effective sample preparation to improve efficiency and reduce frustration.