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This month's LC?GC Europe features the first instalment of a brand-new column. Following many requests from readers, "Practical Data Handling" will concentrate on chemometrics.

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The authors discuss zero-, first- and second-order data and describe the advantages of using second-order chromatographic data compared with the more traditional univariate or multivariate calibration. They demonstrate how its use can uncover much more information from chromatograms and spectra.