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PerkinElmer, Inc., a global leader in Health Sciences and Photonics, today announced the acquisition of Avalon Instruments Limited, based in Belfast, Northern Ireland. The acquisition expands and complements PerkinElmer?s Molecular Spectroscopy product portfolio through adding a family of innovative bench-top dispersive Raman spectrometers.

News All the news from September 2006 Opinion Zosimus calls for a restructuring of the academic year to prevent final examinations falling in the height of the hayfever season. Market Trends & Analysis Glenn Cudiamat reports on dissolution testing and its importance to the pharmaceutical and other industries. Country Focus This month we look at the recent analytical activities of Germany and Austria. Determination of Chloramphenicol in Food using Automated Solid-Phase Extraction and LC-MS Norbert Helle and Kaj Peterson Q&A Andrew Tipler, senior scientist at the chromatography business unit of PerkinElmer Instruments talks to The Column about thye new Clarus 600 gas chromatograph. Supplies and Services

Ted Szczerba and Francis Mannerino, Regis Technologies, Inc.

Applied Biosystems has joined the Genographic Project as a supporting sponsor for the generation of one of the world's largest databases of information, which will reveal the sources of humankind's diversity. The company has signed a multi-year agreement to provide laboratory research equipment and services to each of the ten participating global research centres. The terms of the agreement were not disclosed.

An experimental design can be considered as a series of experiments that, in general, are defined a priori and allow the influence of a predefined number of factors in a predefined number of experiments to be evaluated.

Sigma-Aldrich Corp. (St. Louis, Missouri) has acquired Pharmorphix, Ltd. (Cambridge, United Kingdom) that offers solid-form research services to pharmaceutical and biotech markets. Terms of the acquisition were not disclosed.

Now there's light in the "black hole" - of a brief case. German-based international leather and bag specialist BREE has created the first illuminated business handbag with Smart Surface Technology. Bree put their trust in innovative solutions. They say, "We had been toying with the idea of illuminating the dark insides of handbags for quite some time, but lacked an elegant solution which not only met our traditionally high demands with regard to style and function, but was also technically feasible."

In month's issue features two new articles entitled "Microparallel LC Methods for the Analytical Laboratory" and "Testing Tap Water with HPLC."

An isocratic HPLC method for the determination of phenol and nitrophenols (4-nitrophenol, 2-nitrophenol, 4,6-dinitro-o-cresol and 2,4-dinitrophenol) has been developed and validated using 2-chlorophenol as internal standard (IS) and a monolithic column in tap water samples. Prior to HPLC, the method requires solid-phase extraction (SPE) using polymeric Lichrolut EN cartridges. The method development involved the study of methanol and acetonitrile as organic modifiers, pH and flow-rate using a Chromolith RP-18e (150 mm x 4.6 mm i.d.) column. After comparing the performance of the separations obtained with both organic modifiers, the optimum separation of these compounds was achieved using 50 mM acetate buffer (pH 5.0)-acetonitrile (80:20, v/v) as mobile phase, 3 mL min21 flow-rate and UV detection at maximum absorbance wavelength. Under these conditions, all analytes were separated (Rs . 2.0) in an analysis time of less than 3.5 min and the most important validation parameters were evaluated. The recoveries obtained in the accuracy test for all phenols studied were in the 90-112% range using a preconcentration factor of 40, and the intraday and interday precisions [expressed as coefficient of variation (CV)] were smaller than 15%. Finally, the proposed method was applied to wastewater samples from several industries.

Waters Corporation announced today that it will work with Applied Biosystems/MDS SCIEX to develop Waters ACQUITY UPLC System software controls for use with Applied Biosystems/MDS SCIEX's Analyst software.

Waters Acquires Thermometric For $2.5 Mln

The Pittsburgh Conference announced today Dr. Charles M. Lieber will deliver a plenary lecture entitled Nanowire Nanoelectronic Devices for Detection of and Interfacing to Biological Systems at Pittcon 2007, February 25 ? March 2, 2007, at McCormick Place in Chicago, IL. The plenary lecture will kick off the Pittcon 2007 Technical Program on Sunday, February 25, 2007.

Waters Corp.'s continued focus on chromatography and mass spectrometry continues to generate strong returns, according to a recent report from Morningstar.

Cohesive Technologies Inc. announced today that it has entered into a collaborative agreement with Mayo Clinic to increase patient sample throughput and improve data quality using Cohesive's proprietary turbulent flow chromatography (TurboFlow? technology) systems for clinical assays using tandem mass spectrometry (MS/MS).

Advanced Chemistry Development, Inc., (ACD/Labs) today announced an exciting collaboration with GlaxoSmithKline (GSK) that is focused on the creation of a specially adapted algorithm for predicting solubility in aqueous DMSO solution as well as related enhancements to ACD/Labs? pKa and aqueous solubility prediction algorithms.

W.R. Grace & Co. is increasing its presence in China with the creation of a subsidiary and technical service center in Shanghai and the expansion of an office in Guangzhou.

Daiso has opened a new subsidiary in the USA with the acquisition of the High Pressure Liquid Chromatography business from Essential Life Solutions.

Sigma-Aldrich Corp. has acquired Pharmorphix Ltd., a privately held firm based in Cambridge, U.K., that offers solid-form research services to pharmaceutical and biotech markets. Terms of the acquisition, paid in cash, weren't disclosed.

Airgas, Inc. today announced that it has reached a definitive agreement to acquire the assets and operations of Houston, TX-based Aeriform Corporation, an independent distributor with 29 locations in Texas, Louisiana, Oklahoma, and Kansas. The companies expect to close the transaction by September 1, subject to due diligence, customary closing conditions, and regulatory reviews.

A fresh test conducted by Center for Science and Environment (CSE) has revealed high levels of pesticide content in colas. The revelation comes after the expose conducted three years back, thereby putting the cola giants in dire straits.

News All the news from August 2006 Opinion With the current boom in Internet shopping, Zosimus questions why he can't order a new chromatograph from the web. Market Trends & Analysis Glenn Cudiamat looks at how the new range of fast LC systems is re-energizing the HPLC market. Sample preparation techniques for ion exchange chromatography Peter Jones, Metrohm Uk Ltd. Characterizing aerosols using comprehensive two-dimensional chromatography Tuulia Hyotylainen Non-classical methods in comprehensive two-dimensional gas chromatography Philip J. Marriott and Paul D. Morrison Supplies and Services Q&A Professor Ernst Kenndler from the Institute of Analytical Chemistry at the University of Vienna explains how he uses capillary electrophoresis to help restore museum artefacts.