All News

John Hinshaw updates his glossary of GC terms and techniques.

The author determines the uncertainty in the quantification of four rat liver samples by applying a statistical evaluation.

The guest authors present a strategy for validating a capillary isoelectric focusing method intended to quantitate impurities in a protein drug substance.

Guest author G. William Tindall discusses pH measurements in aqueous solutions and the changes that occur when organic solvent is added.

Guest author Steve Griffin identifies the fundamental problems in capillary manufacturing techniques that cause capillary defects and suggests some corrective actions.

John Hinshaw discusses the measurement of column flow and its interrelationship with carrier-gas velocity.

Leslie Ettre remembers A.J.P. Martin, inventor of partition, paper, reversed-phase, and gas–liquid partition chromatography.

This article provides theoretical background, experimental data, and practical considerations about the effects of organic modifiers on analyte ionization in reversed-phase LC.

John Dolan examines problems associated with adjusting gradients in reversed-phase LC.

The authors studied the retention behavior of reversed-phase HPLC columns under 100% aqueous mobile-phase conditions.

The authors present their observations from developing data-handling software for GC × GC separations.

Ron Majors describes developments reported at HPLC 2002.

Leslie Ettre describes the development and applications of this long-forgotten unit.

John Hinshaw reports about the 25th International Symposium on Capillary Chromatography and Electrophoresis.

Guest authors describe how this validation is performed routinely in their laboratory.

This month's column discusses a performance qualification test designed by PerkinElmer Analytical Instruments (Shelton, Connecticut).

Product release from NLG Analytical...

A fast HPLC method for separating several triglycerides in edible oils with evaporative light scattering detection. (Alltech Associates, Inc.)

Solid-phase extraction of 6-monoacetylmorphine from urine followed by GC analysis. (Phenomenex Inc.)

Automated SPE in combination with large-volume injection GC–MS analysis of semivolatile compounds. (Horizon Technology, Inc.)

SEC analysis of hemoglobin using multiangle light-scattering detection. (Wyatt Technology Corporation)

Analysis of several commercial diet soft drinks using HPLC with a 100% water mobile phase. (ZirChrom Separations, Inc.)

Pesticide analysis using HPLC with postcolumn derivatization. (Pickering Laboratories, Inc.)

Reversed-phase columns retain and separate peptides using MS-friendly mobile-phase additives without compromising peak shape, peak capacity, or resolution. (Waters Corporation)

Replacing sodium chloride with sodium perchlorate in the separation of an antibody-based fusion protein provided the robustness of an otherwise problematic separation method. (Tosoh Biosep LLC)

Analysis of triglycerides using HPLC with evaporative light-scattering detection.

TLC analysis of morphine. (Analtech, Inc.)

LC analysis of phospholipids. (Advanced Separation Technologies Inc. [astec])