Gas chromatography–mass spectrometry (GC–MS) was used to detect the chemical components of natural musk, harvested from forest musk deer at multiple stages of maturity. This research combines metabolomic profiling with biosynthetic pathway analysis to identify potential precursors and enzymes involved in musk biosynthesis.
In the first section of our interview with Jennifer Geddes-McAlister of the University of Guelph, she discusses her feelings on winning the ASMS 2025 Diversity, Equity, Inclusion and Accessibility (DEIA) Mentorship Award.
Researchers at Baylor College of Medicine’s Children's Nutrition Research Center (Houston, Texas) developed and validated a high-throughput extraction and ultrahigh-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method to separate and quantify 39 spinach flavonoid species in 11.5 min.
Two proof-of-concept hydrophilic interaction chromatography HILIC) methods were developed in a joint study conducted by the University of Geneva (Switzerland), Sanofi, and the Waters Corporation—one for disrupting LNPs and retaining the mRNA, and another for detecting only unencapsulated mRNA to assess encapsulation efficiency. LCGC International spoke to Jonathan Maurer, first author of the paper that resulted from this study, about the methods and the efforts that led up to their development.
In the final moments of our interview with Christian Bleiholder of Florida State University, he discusses the mentors from his early scientific career and imparts advice to future mass spectrometrists.
Here is some of the most popular content posted on LCGC International this week.
In the second section of our interview with Christian Bleiholder of Florida State University, he discusses the work he and his undergraduates are working on in the Bleiholder Laboratory.
We recently interviewed Emma Guiberson, winner of the ASMS 2025 Research at PUI Award, about her research, professional background, and what she wishes to impart to the next generation of mass spectrometrists.
Researchers at Andes Ag, Inc. (Alameda, California) established a high-throughput framework for the robust and precise quantification of soil inorganic carbon (SIC) from agricultural soils using gas chromatography (GC).
In the first section of our interview with Christian Bleiholder of Florida State University, he discusses his award-winning research that earned him the ASMS 2025 Ron Hites Awared.
A joint study between the University of Tennessee (Knoxville, Tennessee) and the University of Pennsylvania School of Veterinary Medicine (Philadelphia, Pennsylvania) compared directly measured vitamin K1 (vitK1) concentrations in healthy dogs and dogs with chronic enteropathy (CE) using liquid chromatography tandem mass spectrometry (LC–MS/MS); they also investigated whether supplementation of vitK1 in dogs with CE would significantly increase vitK1 concentrations.
A study by researchers from Bonn-Rhein-Sieg University of Applied Sciences and the University of Duisburg-Essen reported on the development of a GC–IMS method for the detection of nine N-nitrosamines in drinking water.
A study by researchers from Bonn-Rhein-Sieg University of Applied Sciences and the University of Duisburg-Essen reported on the development of a GC–IMS method for the detection of nine N-nitrosamines in drinking water.
A study conducted by the Agriculture Research Centre of Giza, Egypt, and Jilin Agricultural University in China, evaluated the efficacy of stinging nettle extract, nettle smoke, and formic acid in the controlling of Varroa mites, a major threat to honeybee colonies, with a focus on mite infestation reduction, honeybee mortality, and biochemical responses. Gas chromatography–mass spectrometry (GC–MS) was used to identify key bioactive compounds in the stinging nettle extract.
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Peter Boler, Vice President of Marketing at VUV Analytics, explains the importance of vacuum ultraviolet (VUV) detection and new technology that has emerged to support this methodology.
Click here to access the LCGC International May 2025 Europe PDF in an interactive format.
Click here to access the LCGC International May 2025 North America PDF in an interactive format.
An Australian study used pyrolysis coupled to gas chromatography-mass spectrometry (Pyr-GC–MS) to analyze the presence of plastic polymers in commercial and homemade composts. LCGC International spoke to Simran Kaur—a PhD candidate at the Queensland Alliance for Environmental Health Sciences (QAEHS) at The University of Queensland in Woolloongabba, Australia—to find out more about her team’s findings.
Here is some of the most popular content posted on LCGC International this week.
Merck has launched its 2025 Curiosity Cube tour, bringing hands-on STEM experiences to students across the world.
Based on their hypothesis that smelling anxiety chemosignals can, like visual anxiety induction, lead to an increase in odor sensitivity, a joint study between the University of Erlangen-Nuremberg (Erlangen, Germany) and the Fraunhofer Institute for Process Engineering and Packaging (Freising, Germany) combined behavioral experiments, odor profile analysis by a trained panel, and instrumental analysis of odorants (gas chromatography-olfactometry) and volatiles (gas chromatography-mass spectrometry).
Scientists from the University of Santiago de Compostela developed a liquid chromatography quadrupole time-of-flight mass spectrometry (LC–QTOF-MS) operated in data-independent acquisition (DIA) mode for pesticide quantification in agriculturally impacted waters.
A pilot study investigating whether nicotinamide adenine dinucleotide kinase (NADK) expression is selectively diminished in alcohol-associated liver cirrhosis (AC), as well as evaluating its potential as a biomarker for this condition, measured AC and non-AC (NAC). Nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+) levels in human liver samples were measured using liquid chromatography-mass spectrometry (LC-MS).
A joint study between the University of Oklahoma Health Sciences Center (Oklahoma City, Oklahoma) and the UC Davis West Coast Metabolomics Center (Davis, California) identified differentially regulated lipids in type 2 diabetes (T2D) and obesity through the application of reversed-phase liquid chromatography-accurate mass tandem mass spectrometry (RP-LC-accurate MS/MS).
LCGC EAB member Paul Ferguson has been named a professor by special appointment at the Faculty of Science at the University of Amsterdam.
Polyamides can be difficult to characterize, despite their use in various aspects of everyday life. Vrije Universiteit Amsterdam researchers hoped to address this using a reversed-phase liquid chromatography (RPLC)-based approach.
Saba Aslani from the University of Texas at Arlington spoke to LCGC International about a collaborative project with Northwestern University, the University of Hong Kong, and BioTools, Inc., investigating mirror-image cyclodextrins using ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) and vibrational circular dichroism (VCD).
In the final section of our interview with Vilmos Kertesz of Oak Ridge National Laboratory, he imparts the most important lessons he would like future generations of scientists to learn.
In the penultimate section of our interview with Vilmos Kertesz of Oak Ridge National Laboratory, he reflects on the people who guided him throughout his scientific career.
In the third part of our interview with Vilmos Kertesz of Oak Ridge National Laboratory, he discusses his time creating new liquid extractions and his feelings on seeing his work used around the world.
