Gas Chromatography (GC)

Researchers at Swansea University (Swansea, Wales, United Kingdom) are using GCMS-TD technology to analyze the concentrations of volatile organic compounds (VOCs) in breath.

Engineers at the Massachusetts Institute of Technology (MIT), in Cambridge, Massachusetts, are designing a tiny sensor that can detect minute quantities of hazardous gases more efficiently and quickly than current devices on the market.

Screening for important factors during method optimization or in robustness testing involves two-level screening designs, such as fractional factorial and Plackett–Burman designs, as described in Part 1. This second part on screening designs discusses the experimental protocol for executing these designs and the data analysis of their results.

During the last several years, the GC market has experienced strong growth in part because of new product introductions, growth in the petroleum sector, and increased opportunities in various geographies. To shed light on and determine the many realities and trends of the current GC instruments market, Strategic Directions International conducted a global survey of gas chromatography (GC and GC-MS) users. The survey was designed for individuals who are currently using a wide array of GC instruments and consumables, including aftermarket software, components, and accessories. The data were collected over the phone and by an internet-based survey. When necessary, the internet survey was followed up with direct telephone interviews of the appropriate respondents to further clarify answers.

The authors use GPC coupled online to multiangle laser light scattering, refractive index, and ultra violet (UV) detectors for the characterization of Acacia gum (gum arabic).

Since 1950, Pittcon has served as a platform for recognition of scientists whose pioneering research helped make dramatic advances in their specific disciplines. The Spectroscopy Society of Pittsburgh (SSP), one of the two sponsoring societies that organize Pittcon, first presented its Spectroscopy Award in 1957 and has recognized the work of leading spectroscopists since. The second Pittcon cosponsor, the Society for Analytical Chemists of Pittsburgh (SACP), began recognizing leading analytical chemists with their annual award in 1978. The list of award recipients is a "who's who" of scientists, including Nobel Laureates, whose work advanced scientific discoveries at an amazing pace while laying the groundwork for the development of modern day instrumentation in mass spectrometry (MS), inductively couple plasma (ICP), Fourier-transform (FT)-IR, and hyphenated instrumental techniques.

The second part of the series takes a look at what happens to the pneumatic operating conditions and chromatography with GC oven temperature programming of a wide-bore column.

Work done 60 years ago at the University of Innsbruck (Austria), representing the start of gas chromatography, is outlined in this month's column.

Comprehensive GCxGC was employed for the separation of ICH and USP 1, 2, and 3 pharmaceutical solvents. The significantly improved peak capacity in GCxGC allows a single method for any combination of solvents and mitigates interference due to impurities in the solvents, diluents, analyte matrices, and from column or septum bleed, through the increased separation space.

In this month's "GC Connections" instalment, John Hinshaw discusses computerized pneumatics for gas chromatography. This is the first of a two-part series that reviews computerized pneumatics and some important considerations that arise in the course of normal use.

Since 1950, Pittcon has served as a platform for recognition of scientists whose pioneering research helped make dramatic advances in their specific disciplines. The Spectroscopy Society of Pittsburgh (SSP), one of the two sponsoring societies that organize Pittcon, first presented its Spectroscopy Award in 1957 and has recognized the work of leading spectroscopists every year since. The second Pittcon co-sponsor, the Society for Analytical Chemists of Pittsburgh (SACP), began recognizing leading analytical chemists with their annual award in 1978. The list of award recipients is a "who's who" of scientists, including Nobel Laureates, whose work advanced scientific discoveries at an amazing pace while laying the groundwork for the development of modern day instrumentation, including mass spectrometry, ICP, FT-IR, and hyphenated instrumental techniques. This two-part article will provide a historical perspective on the accomplishments of several Pittsburgh Spectroscopy Award and Pittsburgh Analytical Chemistry Award winners, highlighting some of the work recognized in each decade leading up to Pittcon 2008. Part I will chronicle the years 1957 through 1977 while Part II will highlight the years 1978 through Pittcon 2008.

A study is just beginning in Brisbane, Australia using a mobile gas chromatography and mass spectroscopy to analyze volatile organic compounds (VOCs) detected by a breath scanner.

Indian researchers are studying the affects that EPA and DHA (together known as Omega-3), the two main long-chain polyunsaturated fatty acids found in oily fish and shellfish, may have had on the brain development of prehistoric ancestors.

Natural Products Insider repots that 58 sports supplements have been tested using various chromatography methods, including GC., to test for steroids and stimulants.

The Journal of Clinical Endocrinology & Metabolism reports on Swedish findings of using GC-MS to measure serum and urine levels of testosterone and dihydrotestosterone in young adult men and elderly men.

Anatune, a suppler of chromatography-based instrumentation, is constructing a website for gas chromatographers. Research and application information regarding GC and gas chromatography-mass spectrometry (GC-MS) will be available.

Time reports that Colin Pillinger and his colleague Geraint Morgan have developed a mini GC-MS capable of detecting tuberculosis.

In this month's "GC Connections" installment, John Hinshaw discusses computerized pneumatics for gas chromatography. This is the first of a two-part series that reviews computerized pneumatics and some important considerations that arise in the course of normal use.

Information from guidance documents used in clinical investigations can be very useful to help meet FDA regulations regarding computer security in analytical laboratories.

Gilson, Inc. (Middleton, Wisconsin), an industry leader in purification systems for high performance liquid chromatography (HPLC), solid phase extraction (SPE), and gel permetation chromatography (GPC) clean-up, now offers direct support and sales in the United States.

Thermo Fisher Scientific Inc., a leader in the separation sciences and chromatography industries, announces the launch of its enhanced partner program. The program is designed to support the expansion of the companies' informatics activity via its partners around the globe, the world class program will utilize business partners to better meet customer needs in multiple industries. Thermo Scientific?s informatics offerings include laboratory information management systems, chromatography data systems, and spectroscopy software.

Screening designs are used to screen for important factors during method optimization or in robustness testing. Usually, two-level screening designs, such as fractional factorial and Plackett–Burman designs, are applied. This column discusses the properties of these designs.

Gas chromatography–mass spectrometry (GC–MS) is the most widespread tandem technique in the analytical instrumentation industry. In fact, these systems account for the largest installed base of mass spectrometry instruments.

This month, Chromatography Online's Technology Forum focuses on the topic of Gas Chromatography (GC). Joining us for this discussion is Sky Countryman, GC Product Manager at Phenomenex; Gary Harland, Tandem Quadrupole MS Product Manager at Waters; a Team of Experts from Thermo Fisher Scientific; and Tom Gluodenis and Terry L. Sheehan from Agilent Technologies Life Sciences & Chemical Analysis Group.

Gas chromatography–mass spectrometry (GC–MS) is the most widespread tandem technique in the analytical instrumentation industry. In fact, these systems account for the largest installed base of mass spectrometry instruments.