May 13th 2024
In this edition of The LCGC Blog, Katelynn Perrault and James Harynuk discuss the technological needs one faces when setting up a workstation for chromatography data analysis.
How To Buy Gas Calibration Mixes
July 1st 2005There is a great deal of confusion floating about when it comes to selecting gas mixtures for analytical applications. Questions such as "How is the gas certified?," "What standard should I use?," and "What level of uncertainty is acceptable?" are common concerns heard among those tasked with specifying and using mixtures. In addition, the uncertainty regarding terminology, measurement, safety, and storage can make specifying mixtures a true source of headaches and hassles for any lab manager. The following article provides answers to questions about gas mixtures.
Enhanced Sample Throughput for Environmental Analysis
June 1st 2005As environmental legislation becomes more stringent, the need to deliver quantitative results in shorter times and greater volumes is necessary for routine environmental analysis. Most of the high-throughput screening methods used to analyze pharmaceutical compounds are, however, useless for environmental monitoring. This is because these methods primarily aim to retrieve as much information from a single sample using the broadest range of techniques. The chromatographic separation process is considered to be the bottleneck in the process. This is not the situation for environmental procedures, in which the bottleneck is the sample preparation step and is usually very tedious and time-consuming.
Determining the Hydrocarbon Oil Index in Water using Ultra Fast Gas Chromatography
June 1st 2005This article discusses utra fast gas chromatography as a suitable technique for determining the hydrocarbon oil index in water. The advantages of this technique over conventional GC technology are presented.
New Chromatography Columns and Accessories at the 2005 Pittcon Conference: Part II
April 1st 2005This month's installment of "Column Watch" is the conclusion of a two-part series in which Ron Majors examines the trends in column introductions at Pittcon 2005. Here, he discusses gas chromatography columns, sample preparation products, hardware, and accessories.
Determination of Protease Inhibitors Used in the Treatment of HIV
March 2nd 2005Protease inhibitors are a class of anti-HIV drugs used in combination therapy to block replication of the HIV virus in a person's blood. It is important to monitor the levels of these drugs in the patient since resistance can develop at low levels and at high levels the drug can exhibit toxic effects.
Flow, Pressure and Temperature Calibration: Part 2
March 1st 2005In the concluding part of this series, the effects that column variability has on isothermal capillary gas chromatography is discussed and instrument calibration explored. The goal is to reduce the normal variability that occurs when working with multiple instruments and columns to ensure consistent results.
New Chromatography Columns and Accessories at the 2005 Pittcon Conference: Part I
March 1st 2005Pittcon 2005 - the 56th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy - returned to the Orange County Convention Center, Orlando, Florida, 27 February-4 March 2005. This year's event hosted more than 900 instrument manufacturers and 1aboratory suppliers in more than 2300 booths. In addition to attending the exposition, the conferees were able to listen to numerous oral presentations, view more than 900 posters, check out 38 seminar rooms, or attend one of 150 short courses.
Taming the Regulatory Beast: Regulation versus Functionalism
February 1st 2005The authors discuss the issue of meeting the demands of regulatory compliance whilst ensuring good scientific practice. A number of requirements from 21 CFR Part 11 are cited to demonstrate the importance of applying the principles of risk analysis.
Developments in Preparative-Scale Chromatography Columns and Accessories
December 1st 2004This column focuses on some of the latest developments in preparative-scale columns, bulk packing materials and column hardware designs. Silica, polymeric and other packings are discussed together with the newest monolithic columns.
More Speed, Better Precision, Higher Sensitivity: Why Buy a New Gas Chromatograph?
September 1st 2004This article is an adaptation of one written in the German publication Nachrichten aus der Chemie and discusses how gas chromatography instrumentation, columns and techniques have improved over the past 10–15 years, making even relatively new equipment obsolete for many applications. In particular, the authors look at how older equipment is unsuitable for fast GC, better trace analysis and comprehensive multidimensional GC.