LCGC Interviews

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Populations worldwide are exposed to polychlorinated biphenyls (PCBs) that can be harmful to human health. The Column spoke to David Megson from Ryerson University in Toronto, Canada, about recent developments in assessing human exposure to PCBs and chiral enantiomer fractions (EFs) in the workplace.

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Fundamental Foodomics

Foodomics can help to investigate and solve crucial topics in food science and nutrition from a short- and long-term perspective. LCGC spoke to Alejandro Cifuentes from the Laboratory of Foodomics at the Institute of Food Science Research (CIAL), National Research Council of Spain (CSIC) in Madrid, Spain, about the fundamental importance of foodomics and where the field of food analysis is heading.

Preventing environmental contaminants from getting in to the food chain is of paramount importance to us all. Yelena Sapozhnikova, a Research Chemist at the Agricultural Research Service, United States Department of Agriculture (USDA) in Wyndmoor, PA, USA, spoke to The Column about her research into the development and evaluation of analytical methods for persistent and emerging organic chemical contaminants in food samples.

Marine polychaetes are a common type of annelid worm widely spread in marine environments. Raquel Fernandez from the University of Copenhagen, Denmark, spoke to Aladair Matheson of The Column about her innovative approach to developing an untargeted method to monitor polychaetes and assess their potential use in environmental monitoring of oil spills.

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There is a growing demand in the pharmaceutical industry for fast and selective separation methods to monitor drug behaviour in small-volume biological samples. David S. Hage from the University of Nebraska–Lincoln, USA, has recently developed a series of methods using affinity chromatography and related techniques for this purpose. LCGC interviewed him on this work.

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Persistent organic pollutants (POPs) pose an on-going threat to human health, but are often trapped within environmental samples, thereby making analysis challenging. Bethany Degg of The Column spoke to Lourdes Ramos from the Department of Instrumental Analysis and Environmental Chemistry Institute of Organic Chemistry of the CSIC (Madrid, Spain) about her innovative research on new sample preparation methods for POPs.

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Researchers at the University of Waterloo in Canada are collaborating with clinicians at Toronto General Hospital to develop preclinical and clinical applications of solid-phase microextraction (SPME). Bethany Degg of The Column spoke to Barbara Bojko from the team to find out more.

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Preventing environmental contaminants from getting in to the food chain is of paramount importance to us all. Yelena Sapozhnikova, a Research Chemist at the Agricultural Research Service, United States Department of Agriculture (USDA) in Wyndmoor, PA, USA, spoke to LCGC about her research into the development and evaluation of analytical methods for persistent and emerging organic chemical contaminants in food samples.

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In developing countries, access to medicine is often limited. To make matters worse, widespread counterfeiting often means that even when patients get access to drugs, the drugs are of poor quality. Dr. Mélisande Bernard, of the Agence Générale des Equipements et Produits de Santé, the technical and pharmaceutical service of the public hospital system of Paris, France (Assistance Publique–Hôpitaux de Paris), is helping to address this problem by developing chromatographic methods to detect substandard cardiovascular drugs in Africa. She recently spoke to us about this work.

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Jonathan V. Sweedler, a professor in the Department of Chemistry at the University of Illinois, and the 2015 ANACHEM Award winner, has focused his group’s major research efforts on analytical neurochemistry, developing new measurement tools to characterize small-volume samples for their cell–cell signaling molecules, and applying these technologies to the study of the distribution and dynamic release of neuropeptides, classical transmitters, and other cell–cell signaling molecules from the brain.

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Bryan Vining from SGS Environmental Service (Wilmington, North Carolina, USA) reveals some of the cutting-edge research his team has performed involving dioxin analysis, and proposes some future possibilities for the direction of this field.

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The biopharmaceutical industry continues to expand in response to a demand for novel biopharmaceuticals. José Paulo Mota from the Faculty of Science and Engineering (FCT-UNL) of Universidade Nova de Lisboa and the Institute of Experimental and Technological Biology (IBET), Portugal, has been working on the development of chromatographic techniques to speed up the purification of biopharmaceuticals, specifically adenoviruses. Bethany Degg of The Column spoke to him about his work.

Bethany Degg of The Column spoke to James Neal-Kababick, who is the Founder and Director of Flora Research Laboratories (FRL) in Oregon, USA, about phytoforensic science and his work on analyzing dietary supplements previously recalled by the US FDA.

Benedetto Natalini of the University of Perugia, Italy, spoke to Bethany Degg of The Column about the driving forces in pharmaceutical analysis, including the importance of regulation, chirality, and miniaturization.

Kate Mosford of The Column spoke to Miguel Herrero of the Institute of Food Science Research (CIAL-CSIC) at the Spanish National Research Council, in Madrid, Spain, about his research in foodomics-based approaches, the evolution of food analysis, and the benefits of 2D LC in this application.

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Kate Mosford of The Column spoke to Rosa Perestrelo of Centro de Química da Madeira located in Madeira University, Portugal, about wine analysis. She reveals the science behind winemaking and offers her tips for selecting the best analytical method.

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DNA can be analyzed by many techniques, including electrophoretic techniques such as gel, capillary, and microchip electrophoresis. In this interview Kevin Dorfman, an Associate Professor in the Department of Chemical Engineering and Materials Science at the University of Minnesota in Minneapolis, Minnesota, USA, discusses his research with polymer physics and microfluidic and nanofluidic technologies.

Dr Kevin Cooper of the Institute for Global Food Security at Queen's University Belfast, Northern Ireland, spoke to Kate Mosford of The Column about the importance of accuracy, reliability, and stability in food safety analysis and the role of ultrahigh-pressure liquid chromatography tandem mass spectrometry (UHPLC–MS–MS) in his research.