Liquid Chromatography (LC/HPLC)

The continual increase in sample numbers in busy labs means that it is often difficult for quality control or contract analysis labs to maintain short turnaround times, particularly when instruments are already running at full capacity. To address the need for faster analysis while retaining the quality of separation offered by dedicated amino acid analysers, an improved formulation of sodium citrate based buffers has been developed by Biochrom.

it has been more than 10 years since solvent recycling has been the main subject of an "LC troubleshooting" column, so this month, John Dolan revists this subject.

Fast, reliable measurements of lipophilicity has a great impact on the compounds' selection process at an early stage of dug discovery. The guest columnit examines HPLC methods for this purpose.

Separation instrument techniques are among the most widely used technologies in the analytical instrumentation market. They span the entire industrial and regional marketplace. The lab separations market includes chromatographic techniques such as analytical and preparative HPLC, GC, IC, TLC, flash, and low pressure LC.

Research group: Professor Jan Andersson, Institute of Inorganic and Analytical Chemistry, University of Münster, Münster.

An overview is presented of possible pathways to enhance peak capacity in liquid chromatography (LC). The peak capacity in a chromatographic separation is directly related to the plate number and thus to column length and particle size. Serial coupled columns can be used to obtain long effective column lengths, reaching over 100000 theoretical plates and peak capacities up to 900. Some theoretical considerations are made on column dimensions and particle size and examples are given of high resolution "GC-like" separations in LC using state-of-the-art LC hardware. Recent developments in LC hardware have also enhanced the applicability of two-dimensional LC–LC and comprehensive LCÃ-LC. Both techniques are extremely powerful to unravel complex samples.

This month's installment of "Column Watch" is the first of a two-part series in which Ron Majors examines the trends and highlights in columns and consumables at Pittcon 2007.

A reluctance to make any changes to a validated or compendial method is common, and often well founded.

Modern Liquid Chromatography was the hot topic of the day in a standing room only technical session on the third day of Pittcon 2007. Arranged by Peter W Carr (University of Minnesota) and Stephen G Weber (University of Pittsburgh), the session's favorite subject seemed to be high performance liquid chromatography (HPLC).

For a young scientist, being recognized for your hard work at such an early stage in your career is a tremendous honor.

A topic on everyone's minds these days, especially those of us who traveled by air to get to Pittcon, is Homeland Security.

The Ancient Greeks ate sheep testicles before competitions. Contemporary athletes have designer steroids. What techniques can we use to test our athletes for banned substances?

The 2007 Pittsburgh Analytical Chemistry Award was presented Tuesday morning to Jonathan V. Sweedler, Lycan Professor of Chemistry at the University of Illinois at Urbana/Champaign.

Well-known LCGC Columnists John Dolan and John Hinshaw provide their list of recommended sessions.

Good morning and welcome to LCGC's third and final day of conference coverage from Pittcon 2007.

Well-known LCGC Columnists John Dolan and John Hinshaw provide their list of recommended sessions.

Good morning, fellow Pittcon conferees, and welcome to Day 2 of LCGC North America's ongoing coverage from Pittcon 2007.

Chromatography Forum of Delaware Valley Dal Nogare Award Dr. John W. Dolan was the proud recipient of the Dal Nogare Award at Pittcon 2007, adding another bright note to his illustrious career.

The 2007 Ralph N. Adams Award in Bioanalytical Chemistry was presented to Norman J. Dovichi, Professor of Chemistry at the University of Washington, on Monday afternoon at Pittcon 2007.

Attendees continue to trickle in, as snowstorms around the country continue to disrupt air travel. For those like me who thought, "Chicago in February? Hooray!"

Yesterday, Andrew Tiplerwas going nowhere fast because of airport delays. Today, he was discussing how to accelerate your gas chromatography runs.

Shana Kelley received the Pittsburgh Conference Achievement Award in a ceremony on Monday morning of Pittcon 2007.