Market Profiles

Market profile: Ion chromatography

Market Profile: Solid-Phase Extraction

Solid-phase extraction (SPE) has been commercially available for nearly 25 years and is still finding new applications.

In gas chromatography (GC), the sample vapor passes through the column and separates into its components - a separation that is governed by the distribution between the mobile and stationary phases.

In gas chromatography (GC), the sample vapor passes through the column and separates into its components ? a separation that is governed by the distribution between the mobile and stationary phases.

Market profile of the analytical and life science instrumentation industry.

Ion chromatography (IC) is a similar technique to high performance liquid chromatography (HPLC) except that the detector of choice is usually a conductivity detector.

Market profile of dissolution testing, a mandatory test for the physical evaluation of drugs that are in a solid dosage form such as capsules, tablets, ointments and creams.

The last five years were somewhat tumultuous times for instrument companies. From 2006 through 2008, the market grew rapidly, fueled by proteomics, metabolomics, biomarker research, and other life science applications.

A market profile of Chromatography Data Systems (CDS's) using data extracted and adapted from SDi's recently published Market Analysis and Perspective (MAP) report titled High Performance Liquid Chromatography: Competing Techniques Setting the Bar Higher.

Dissolution testing is a mandatory test for the physical evaluation of solid dosage forms, such as capsules, tablets, ointments, and creams. The most basic form of testing measures the rate of dissolution or solubility of a drug tablet.

Market Profile: UHPLC

A chromatography data system (CDS) is a software program that automates instrument control, data acquisition, data processing, data filtering, data storage, and database management for ion chromatography (IC), high performance liquid chromatography (HPLC), gas chromatography (GC), supercritical fluid chromatography (SFC), and capillary electrophoresis (CE) instrumentation.

In continuous flow analysis (CFA), a sample is injected into a flowing carrier solution passing rapidly through small-bore tubing. The sample is mixed with a reagent, which reacts with the sample to develop a color and determine the sample concentration. The use of carefully controlled flow conditions ensures that the color development reaction is reproducible, so that the color measurement need not wait until the reaction has gone to completion.

UHPLC systems have been shown to provide analysis times of less than 1 min and up to 40 times faster than conventional HPLC systems.

High content screening (HCS) is a high‑throughput method which enables the functional analysis of cells.

The CFA technique of segmented flow analysis (SFA) uses turbulent flow conditions that allow for complete sample dispersion. In contrast to CFA, discrete analyzers keep samples separate throughout the testing process, dispensing precise amounts when required.

With accountability and regulatory compliance being such a large part of the modern laboratory, the necessity for a laboratory information management system (LIMS) cannot be understated.

High-content screening (HCS) is a high-throughput method that enables the functional analysis of cells. HCS plays a vital role for drug discovery applications, including drug targets verification and pathway detection, in both the pharmaceutical and biotechnology industries.

Supercritical fluid chromatography (SFC) makes use of a supercritical fluid, typically carbon dioxide (CO2), instead of an organic or aqueous solvent, to carry the sample through the chromatography column.

With accountability and regulatory compliance being such a large part of the modern laboratory, the necessity for laboratory information management systems (LIMS) cannot be understated.

Flow cytometry is an analytical technique used to examine the physical and chemical properties of cells and microparticles, including beads.

Supercritical fluid chromatography (SFC) makes use of a supercritical fluid, typically carbon dioxide, instead of an organic or aqueous solvent, to carry the sample through the chromatography column.

Flow cytometry is an analytical technique utilized to examine the physical and chemical properties of cells and microparticles, including beads. This method exploits a wide range of disciplines to elucidate information such as size, shape, DNA content, surface receptors and membrane permeability as well as to count the cells in a sample.

Although the Indian economy has garnered world attention with its importance in the information technology and service sectors, the country has recently become far more prominent in industries that are strong sources of demand for analytical instrumentation.

Life science research has been a driving force behind the $40 billion analytical instrument market growth over the last decade, resulting in new products, applications, markets, and companies.

Gas chromatography?mass spectrometry (GC?MS) combines a gas chromatographic front-end separation with a mass spectrometer. For the most part, the gas chromatographs and mass spectrometers used are modular in design and relatively easily separable. GC?MS is the most widespread tandem technique in the analytical instrumentation industry, which are employed across many different industries, particularly for environmental, chemical and toxicological applications.

Gas chromatography-mass spectrometry (GC?MS) combines a gas chromatographic front-end separation with a mass spectrometer. For the most part, the gas chromatographs and mass spectrometers used are modular in design and are relatively easily to separate. GC?MS is the most widespread tandem technique in the analytical instrumentation industry. The systems are employed in many different industries, particularly for environmental, chemical, and toxicological applications.

Preparative chromatography has been widely used as a purification technique for many years, particularly in the pharmaceutical industry. Joining us for this forum are Frédéric Cheviron of Chiral Technologies Europe, J.T. Presley of Phenomenex, and Jean Bléhaut of Novasep.

Automating the DNA sequence process is made possible by the use of fluorescent tags. With fluorescent dyes, the entire experiment can be performed in a single solution instead of four different ones.