Market Profiles

Ultrahigh-pressure liquid chromatography (UHPLC) systems are designed to take full advantage of sub-2-?m particles, which yield higher resolution and increased sensitivity.

Market Profile: Flash Chromatography

Automating the DNA sequencing process is made possible by the use of fluorescent tags.

Automating the DNA sequence process is made possible by the use of fluorescent tags. With fluorescent dyes, the entire experiment can be performed in a single solution instead of four different ones.

Solid-phase extraction (SPE) has been commercially available for nearly 25 years and is still finding new applications. Growth of this technique appears to be largely a function of the vendors' capability to provide specific application support, especially in clinical sciences, pharmaceuticals, toxicology, pesticides and residues analysis.

Flash chromatography has become a popular method of normal-phase separation through purification.

Market profile: Ion chromatography

Market Profile: Solid-Phase Extraction

Solid-phase extraction (SPE) has been commercially available for nearly 25 years and is still finding new applications.

In gas chromatography (GC), the sample vapor passes through the column and separates into its components - a separation that is governed by the distribution between the mobile and stationary phases.

In gas chromatography (GC), the sample vapor passes through the column and separates into its components ? a separation that is governed by the distribution between the mobile and stationary phases.

Market profile of the analytical and life science instrumentation industry.

Ion chromatography (IC) is a similar technique to high performance liquid chromatography (HPLC) except that the detector of choice is usually a conductivity detector.

Market profile of dissolution testing, a mandatory test for the physical evaluation of drugs that are in a solid dosage form such as capsules, tablets, ointments and creams.

The last five years were somewhat tumultuous times for instrument companies. From 2006 through 2008, the market grew rapidly, fueled by proteomics, metabolomics, biomarker research, and other life science applications.

A market profile of Chromatography Data Systems (CDS's) using data extracted and adapted from SDi's recently published Market Analysis and Perspective (MAP) report titled High Performance Liquid Chromatography: Competing Techniques Setting the Bar Higher.

Dissolution testing is a mandatory test for the physical evaluation of solid dosage forms, such as capsules, tablets, ointments, and creams. The most basic form of testing measures the rate of dissolution or solubility of a drug tablet.

Market Profile: UHPLC

A chromatography data system (CDS) is a software program that automates instrument control, data acquisition, data processing, data filtering, data storage, and database management for ion chromatography (IC), high performance liquid chromatography (HPLC), gas chromatography (GC), supercritical fluid chromatography (SFC), and capillary electrophoresis (CE) instrumentation.

In continuous flow analysis (CFA), a sample is injected into a flowing carrier solution passing rapidly through small-bore tubing. The sample is mixed with a reagent, which reacts with the sample to develop a color and determine the sample concentration. The use of carefully controlled flow conditions ensures that the color development reaction is reproducible, so that the color measurement need not wait until the reaction has gone to completion.

UHPLC systems have been shown to provide analysis times of less than 1 min and up to 40 times faster than conventional HPLC systems.

High content screening (HCS) is a high‑throughput method which enables the functional analysis of cells.

The CFA technique of segmented flow analysis (SFA) uses turbulent flow conditions that allow for complete sample dispersion. In contrast to CFA, discrete analyzers keep samples separate throughout the testing process, dispensing precise amounts when required.

With accountability and regulatory compliance being such a large part of the modern laboratory, the necessity for a laboratory information management system (LIMS) cannot be understated.

High-content screening (HCS) is a high-throughput method that enables the functional analysis of cells. HCS plays a vital role for drug discovery applications, including drug targets verification and pathway detection, in both the pharmaceutical and biotechnology industries.