November 1st 2024
In this article, the authors describe a simple workflow to develop a GC×GC method for a specific sample upon initial use, with the aim of decreasing the time to accomplish functional workflows for new users.
October 30th 2024
September 26th 2024
Analyzing Extractables in Pharmaceutical Packaging Material with 2D-GC-TOF-(MS)
August 26th 2023As part of the upcoming Recent Advances in Gas Chromatography meeting, Nicholas Morley will look at how two-dimensional gas chromatography-time-of-flight-mass spectrometry analyzes pharmaceutical packaging.
GCxGC/TOF-MS and GC-TOF-MS Comparisons To Be Made at Science and Industry Museum
August 26th 2023Two-dimensional gas chromatography time-of-flight mass spectrometry (GCxGC/TOF-MS) and gas chromatography–time-of-flight mass spectrometry (GC-TOF-MS), two different gas chromatography techniques, will have their procedures and uses compared at the Science and Industry Museum, in Manchester, UK.
A Modern Mineral Oil Hydrocarbon Analysis
August 1st 2023Giorgia Purcaro of the University of Liège discusses the advantages offered by the liquid chromatography–comprehensive multidimensional gas chromatography time-of-flight mass spectrometer/flame ionization detector (LC–GCxGC–TOF-MS/FID) method in the analysis of mineral oil.
GC✕GC–TOF-MS Helps Quantify Pesticides in Water Susceptible to Contamination
April 28th 2023Pesticides in local surface and groundwaters were purified and enriched with solid-phase extraction, then analyzed using multidimensional gas chromatography coupled to mass spectrometry, with the results compared to those found by gas chromatography–quadrupole mass spectrometry.
The LCGC Blog: GC×GC…Why Bother?
January 3rd 2023Comprehensive two-dimensional gas chromatography (GC×GC) is becoming increasingly popular, but is still not used as commonly as it could be. That likely means that the technique is still not widely understood. This article is intended to begin demystifying GC×GC by presenting a simple explanation of how it works and its major benefits.
Separation Science: The State of the Art: Multidimensional Gas Chromatography Moves Forward
December 1st 2022In this extended special feature to celebrate the 35th anniversary edition of LCGC Europe, key opinion leaders from the separation science community explore contemporary trends in separation science and identify possible future developments.
Rising Stars of Separation Science: Katelynn Perrault
July 8th 2021This month we interview Katelynn Perrault, Associate Professor of Forensic Sciences and Chemistry at Chaminade University of Honolulu in Honolulu, Hawaii, about her work translating 1D GC methods to effective comprehensive 2D GC (GC×GC) methods for forensic applications and the benefits that GC×GC offers the analyst.
Beat the Heat: Cold Injections in Gas Chromatography
July 1st 2020In gas chromatography, heating the sample in the inlet can lead to sample losses and loss of quantitative reproducibility, but these problems can be avoided using cold sample introduction. This article describes various types of cold injection and how they can benefit the analyst.
Recent Application and Instrumental Trends in Comprehensive Two-Dimensional Gas Chromatography
April 1st 2020This critical review describes recent applications and instrumental trends in comprehensive two-dimensional gas chromatography (GC×GC), with particular (though not exclusive) attention to the period 2018–2019 and that the concept of GC×GC is inherently simple. The maturity of GC×GC and future developments are also discussed.
GC×GC–MS for Forensic Analysis
December 17th 2018GC–MS is considered the gold standard in forensic trace evidence analysis because of its ability to chromatographically separate and analyze components in mixtures. Although GC×GC–MS has been used extensively in the oil and petroleum and flavour and fragrance industries, it has not been fully explored in the forensic sector. However, forensic scientists often encounter highly complex samples that would benefit from the capabilities of GC×GC–MS, such as, sexual lubricants, automobile paints, and tyres. GC×GC–MS analysis can allow for the deconvolution of coeluted components while providing increased sensitivity of minor components to help benefit any forensic laboratory.