Multidimensional GC

There are several key benefits to using multidimensional GC techniques in routine analysis. An examination of mineral oil analysis in food reveals the utility of these techniques.

Giorgia Purcaro of the University of Liège discusses the advantages offered by the liquid chromatography–comprehensive multidimensional gas chromatography time-of-flight mass spectrometer/flame ionization detector (LC–GCxGC–TOF-MS/FID) method in the analysis of mineral oil.

Researchers compare the separation efficiency of olefins and paraffins using stationary phases containing silver(I) ions in ionic liquid (IL) and polymeric ionic liquid (PIL) matrices for gas chromatography techniques.

The retention parameters defined in gas chromatography (GC) analysis using multiple temperature programs were comparable to those determined using isothermal GC measurements.

Innovative gas chromatography (GC) study combines computer vision and chromatographic fingerprinting to uncover diagnostic signatures in food volatilome.

Pesticides in local surface and groundwaters were purified and enriched with solid-phase extraction, then analyzed using multidimensional gas chromatography coupled to mass spectrometry, with the results compared to those found by gas chromatography–quadrupole mass spectrometry.

A new study has demonstrated a practical solution for the reliable compound-specific isotope analysis (CSIA) of trace-level pollutants in complex environmental samples, using 2DGC-IRMS.

LCGC Europe spoke to Giorgia Purcaro from the University of Liège in Belgium, about her work investigating mineral oil hydrocarbons (MOH) using GCxGC and the practical advantages that a novel LC–GCxGC–TOF-MS/FID method offers the analyst.

"GC Connections" presents the column's annual review of new developments made in the field of gas chromatography, made available in 2022–2023.

The 20th International GC×GC Symposium will take place from 28 May–1 June 2023, and will be held in Canmore, Alberta.

GC×GC is now a well-established technique, but it is still underutilized in many settings.

This article is intended to begin demystifying GC×GC by presenting a simple explanation of how it works and its major benefits.

Understanding the relationship between selectivity and retention is key to realizing excellent gas chromatographic separations.

Two-dimensional gas chromatography (GC×GC) and chemometrics are leading the way in new strategies on multivariate data analysis. Using GC×GC in untargeted analysis reveals how far the technique has advanced the field of separation science.

Comprehensive two-dimensional gas chromatography (GC×GC) is becoming increasingly popular, but is still not used as commonly as it could be. That likely means that the technique is still not widely understood. This article is intended to begin demystifying GC×GC by presenting a simple explanation of how it works and its major benefits.

In this extended special feature to celebrate the 35th anniversary edition of LCGC Europe, key opinion leaders from the separation science community explore contemporary trends in separation science and identify possible future developments.

When should multidimensional GC approaches be used for analyzing complex samples and analytes?

A TD–GC×GC–TOF-MS method for malodour detection

New approaches to sample preparation are being developed for microbial metabolomics to address the inherent complexity of this type of analysis.

The benefits that GC×GC–TOF-MS with tandem ionization and chemometrics offer for fragrance profiling and authenticity evaluation.

This month we interview Katelynn Perrault, Associate Professor of Forensic Sciences and Chemistry at Chaminade University of Honolulu in Honolulu, Hawaii, about her work translating 1D GC methods to effective comprehensive 2D GC (GC×GC) methods for forensic applications and the benefits that GC×GC offers the analyst.

LCGC Europe spoke to Yada Nolvachai about a new approach that offers “super-resolution” for comprehensive two‑dimensional gas chromatography (GC×GC) methods.

In the present research, similar chromatography fingerprints were obtained using finely-tuned cryogenic-modulation (CM) and flow-modulation (FM) comprehensive two-dimensional gas chromatography–mass spectrometry (GC×GC–MS) experimental conditions.

In gas chromatography, heating the sample in the inlet can lead to sample losses and loss of quantitative reproducibility, but these problems can be avoided using cold sample introduction. This article describes various types of cold injection and how they can benefit the analyst.

This critical review describes recent applications and instrumental trends in comprehensive two-dimensional gas chromatography (GC×GC), with particular (though not exclusive) attention to the period 2018–2019 and that the concept of GC×GC is inherently simple. The maturity of GC×GC and future developments are also discussed.