Adjusting Conditions for a Routine Reversed-Phase HPLC Assay, Part 2: Changing Separation Conditions

June 1, 2005
Lloyd R. Snyder

,
Ronald E. Majors

,
John W. Dolan
John W. Dolan

John Dolan has been writing "LC Troubleshooting" for LCGC for over 20 years. One of the industry's most respected professionals, John is currently the Vice President of BASi Northwest Laboratory, McMinnville, Oregon and a principal instructor for LC Resources, Walnut Creek, California. He is also a member of LCGC's editorial advisory board.

LCGC Europe

LCGC Europe, LCGC Europe-06-01-2005, Volume 18, Issue 6
Page Number: 324–329

Columns | <b>Column: Column Watch</b>

In the last part of this series, the authors provide a technical review of the means for method adjustment and the pertinent regulations concerning the required validation of adjusted methods.