In part 1 of "Conversations with Michael Dong," LCGC column editor Michael Dong explains basic drugs and why most drugs are basic rather than acidic.
|Articles|November 1, 1999
- November 1999
- Volume 17
- Issue 11
- Pages: 1016–1019
Cleaning Validation
Author(s)Ira S. Krull, Michael E. Swartz
Krull and Swartz examine validating cleaning methods for pharmaceutical manufacturing equipment and look at general requirements and specific cleaning procedures, sampling types, and analytical methods.
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This month's column looks at validating cleaning methods for pharmaceutical manufacturing equipment. Krill and Swartz discuss general requirements and specific cleaning procedures, sampling types, and analytical methods.
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A novel SFC–QTOF-MS method accurately detected 10 drugs in oral fluid, matching LC–MS/MS in 83 DUID cases while reducing run time by 42% and organic solvent use by 81%.
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