LCGC Asia Pacific
The performance of lubricating oil is significantly degraded by the presence of fuel contaminants such as gasoline and diesel. Recycled oil is particularly susceptible to this form of contamination. Consequently, producers and distributors of lubricating oil must go to great lengths to ensure the levels of fuel contamination are kept to a safe limit (typically 4–5%) in these products.
The Application Notebook
The continual increase in sample numbers in busy labs means that it is often difficult for quality control or contract analysis labs to maintain short turnaround times, particularly when instruments are already running at full capacity. To address the need for faster analysis while retaining the quality of separation offered by dedicated amino acid analysers, an improved formulation of sodium citrate based buffers has been developed by Biochrom.
LCGC Asia Pacific
Bob Wiedemer, Grace Davison Discovery Sciences
LCGC Europe
Gas chromatography (GC) coupled to time-of-flight mass spectrometry (TOF-MS) offers unique solutions for various analytical applications including the analysis of food quality, authenticity and safety markers. This article provides a general overview of TOF-MS basic features, highlighting its advantages and limitations compared with GC using conventional mass analysers. Examples of recent results obtained for selected food contaminants and flavour components are described to illustrate the potential of this recently introduced technique.
The Application Notebook
The analysis of peptides and additives using a new HPLC innovative column technology, Pathfinder, was shown. For the analysis of flavours in lemon juice GC–MS with a new MS library, FFNSC, with linear retention indices was used.
The Application Notebook
Soft drink formulas often include preservatives, artificial sweeteners, flavours or caffeine in their list of ingredients. Using the Acclaim OA column, as many as eight common additives may be determined in a single run. Many of these additives are hydrophilic organic acids for which this column was designed. Notably, benzoate and sorbate, which do not resolve on C18 columns at low pH, are fully separated.
The Application Notebook
Column lifetime is a more and more important issue when developing an analytical method for HPLC. Besides sample treatment, column cleaning and storage, operational parameters of the analytical method will have an influence on column lifetime. This question may not always be addressed early enough in the methods development process.
The Application Notebook
Protease inhibitors are a class of anti-HIV drugs used in combination therapy to block replication of the HIV virus in a person's blood. It is important to monitor the levels of these drugs in the patient since resistance can develop at low levels and at high levels the drug can exhibit toxic effects.
The Application Notebook
Maltodextrin is an easily digested carbohydrate made from corn starch...
The Application Notebook
VENTURE A affinity columns utilize ICEtechTM surface passivation technology...
The Application Notebook
Polymeric monolithic stationary phases offer an alternative to the classical microparticulate sorbents...
The Application Notebook
GC column bleed has been postulated to be caused by "backbiting" of the siloxane chain and volatility of noncrosslinked oligimers...
The Application Notebook
Phytosterols and stanols (hydrogenated phytosterols) are naturally occurring substances?
The Application Notebook
The current concern over acrylamide levels in food has unexpectedly brought amino acid analysis to the forefront . . .
