Application Notes: Industrial
Performance Gains Using Hydrogen Carrier Gas in Refinery Gas Analysis
September 1st 2008Escalating costs and increasing demands for helium, coupled with diminishing helium supply, have given rise to the investigation and use of hydrogen as an alternate choice of carrier gas for use in gas chromatography (GC) applications. This application note illustrates that the use of hydrogen as a carrier gas as an alternative to helium in refinery gas applications is not only possible, but also results in improved performance and higher sample throughput.
Real-Time Response to Bacteria Infection of Bioethanol Fermentation Using a Short Rezex™ ROA Column
September 1st 2008Political priorities as well as economic interests have fueled a dramatic growth in the biofuel industry, due much in part to research funding and tax incentives. Currently the world's ethanol production is estimated to be over 16 billion gallons a year. This number is expected to increase in the next few years, reaching an estimated yearly production of 20 billion gallons by 2012. Today, many ethanol producers add fermentors to expand their production capacity. In order to continue using existing HPLC equipment for the increased monitoring, increased analytical throughput is needed.
SELS - Solvent Enhanced Light Scattering
September 1st 2008Viscotek has been a strong advocate of good chromatography as a prerequisite for GPC (Gel Permeation Chromatography) data accuracy. Our recent work in application development has been driven by extremely difficult samples from industrial, biopharmaceutical, and academic sources. These samples present challenges ranging from sample solubility, column adsorption, as well as detection issues. This report will attempt to highlight a new approach that could be very helpful in certain advanced GPC applications.
SELS — Solvent Enhanced Light Scattering
June 1st 2008Viscotek has been a strong advocate of good chromatography as a prerequisite for GPC (Gel Permeation Chromatography) data accuracy. Our recent work in application development has been driven by extremely difficult samples from industrial, biopharmaceutical, and academic sources. These samples present challenges ranging from sample solubility, column adsorption as well as detection issues. This report will attempt to highlight a new approach that could be very helpful in certain advanced GPC applications.
Determination of Urea and Allantoin in Cosmetics
June 1st 2008Urea and allantoin are added to cosmetic products for skin protection and regeneration, especially for the treatment of dry skin, and analyzed for QC purposes. As polar compounds, they are not ideal for reversed-phase HPLC separations. Neutral hydrophilic compounds like urea and allantoin are best analyzed by hydrophilic interaction chromatography (HILIC). Traditional HILIC columns use silica modified with a hydrophilic group such as diol or cyano. Analytes are adsorbed and subsequently eluted with mobile phases containing high percentages of organic solvent (>75%).