Application Notes: Sample Prep
Automated Phosphopeptide Enrichment from Complex Mixtures
Automated phosphopeptide enrichment from cell lysates with Fe(III)-NTA enables the identification of thousands phosphopepides with high reproducibly and selectivity.
Ion Mobility Mass Spectrometry Phosphopeptide Analysis
Automated phosphopeptide enrichment and ion mobility mass spectrometry (IMS-MS) enables detailed analysis of structural effects of site-specific phosphorylation.
Streamlining DAR Determination for ADCs
Automated Antibody Drug Conjugate (ADC) purification and deglycosylation increases reproducibility and simplifies drug-to-antibody ratio (DAR) determination
Host Cell Protein Analysis
Improved host cell protein analysis using highly reproducible and scalable automated sample digestion and fractionation ahead of LC–MS coupled with iterative MS–MS
Extraction of Synthetic Benzodiazepines from Urine
The hydrolysis and SPE steps were combined for designer and pharmaceutical benzodiazepines from urine along with a fast quantitative LC–MS/MS method.
Comparing SLE Sorbents for Steroids from Plasma
A low-level extraction of steroids using Novum PRO SLE is performed and compared with another SLE product for the baseline cleanliness.
Hydrocarbon Fractionation Using Enviro-Clean Fusion®Ag+
This application note outlines the fractionation of hydrocarbons into aliphatic and aromatic fractions using UCT’s new silver-phase EPH fractionation cartridges.
Analysis of Trace PFAS Vapours in Air
Sampling and analysis of a challenging range of trace-level volatile & semi-volatile vapours of per- & polyfluorinated alkyl substances (PFAS) in air using TD–GC–MS
Analysis of Cannabinoids in Hemp and Cannabis
A simple and robust method for the detection of 16 cannabinoids in hemp and cannabis samples using a rugged isocratic HPLC method coupled with UV detection.
Analysis of Synthetic Cannabinoids in Urine v2
A solid-phase extraction method utilized to extract 19 synthetic cannabinoids produced recoveries in the range of 85–110% with corresponding RSD values of less than 5%.