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Chromatography Simplified: Maximizing the Power of PDA Data via Fully Integrated CDS Spectral Processing Tools Combustion Ion Chromatography: The What, How, Why, & Where How to Do More with Less: All Biopharmaceutical Batch Processes Can Benefit from Multi-Column Chromatography Lessons from ChromTalks 2022 An Examination of Your Extraction Knowledge

Chromatography Simplified: Maximizing the Power of PDA Data via Fully Integrated CDS Spectral Processing ToolsCombustion Ion Chromatography: The What, How, Why, & WhereHow to Do More with Less: All Biopharmaceutical Batch Processes Can Benefit from Multi-Column ChromatographyLessons from ChromTalks 2022An Examination of Your Extraction Knowledge

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Application Notes: Sample Prep

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Scaling for Efficiency and Throughput: LC Method Optimization with Notes on Selectivity and Preparative LC

April 15, 2022

Executive Summary

MHC-Associated Peptide Purification for Immunopeptidomics

April 13, 2022

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Automated MHC-I is associated peptide enrichment using the Agilent AssayMAP Bravo platform with large-capacity Protein A cartridges for immunopeptidomics analysis.

Quantification and Characterization of Biotherapeutics Proteins

April 13, 2022

Sponsored Content

The AssayMAP Bravo was used to purify, digest, and clean up antibodies from 96 cell culture supernatants with high reproducibility and minimal labor prior to LC–MS.

Intact Antibody and Subunit Mass Determination

April 13, 2022

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Intact and subunit antibody mass determination was streamlined using automated purification and enzymatic cleavage and deglycosylation of immobilized antibodies.

Assessing Multiple CQAs for Monoclonal Antibodies v2

April 13, 2022

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Automated sample prep and LC–MS peptide mapping approach to characterize and quantify multiple monoclonal antibody (mAb) critical quality attributes (CQAs)

Automated Phosphopeptide Enrichment from Complex Mixtures

April 13, 2022

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Automated phosphopeptide enrichment from cell lysates with Fe(III)-NTA enables the identification of thousands phosphopepides with high reproducibly and selectivity.

Ion Mobility Mass Spectrometry Phosphopeptide Analysis

April 13, 2022

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Automated phosphopeptide enrichment and ion mobility mass spectrometry (IMS-MS) enables detailed analysis of structural effects of site-specific phosphorylation.

Streamlining DAR Determination for ADCs

April 13, 2022

Sponsored Content

Automated Antibody Drug Conjugate (ADC) purification and deglycosylation increases reproducibility and simplifies drug-to-antibody ratio (DAR) determination

Host Cell Protein Analysis

April 13, 2022

Sponsored Content

Improved host cell protein analysis using highly reproducible and scalable automated sample digestion and fractionation ahead of LC–MS coupled with iterative MS–MS

Extraction of Synthetic Benzodiazepines from Urine

March 30, 2022

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The hydrolysis and SPE steps were combined for designer and pharmaceutical benzodiazepines from urine along with a fast quantitative LC–MS/MS method.