John Chasse

Articles by John Chasse

A recent report from Frost & Sullivan predicts that the expanding use of chromatography in pharmaceuticals, especially in drug development and clinical research, coupled with the food and beverage industry’s heavy reliance on chromatography for quality control, is expected to accelerate market expansion to $6.60 billion in 2028.

Detecting Dimetridazole in Chicken Eggs and Tissue with HPLC-MS/MS

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Researchers at the Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation have developed a high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) method for the precise detection of dimetridazole (DMZ) and its metabolite 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMNI).

Research by Himanshi Upadhyaya & John V. Goodpaster of the Department of Chemistry and Chemical Biology, Indiana University Indianapolis has focused on using an odor-permeable membrane device (OPMD) to determine any changes in the odor of dynamite and have utilized gas chromatography–mass spectrometry in negative chemical ionization mode in all analysis.

Researchers at the University of Wolverhampton have utilized gas chromatography-mass spectrometry (GC-MS) in their efforts to create new scent enrichments in their efforts to trigger mating behaviors of zoo-housed lemur species.

Researchers have evaluated the possibility of analyzing finger sweat through liquid chromatography-mass spectrometry (LC-MS) to ensure medication adherence and as a semi-quantitative tool in therapeutic drug management assessment and report positive results.

A technique to measure total phenolic content (TPC) in vegetable oils through analysis of images captured by a cellphone may prove to be easier to utilize than the traditional methods of ultraviolet/visible (UV-vis) spectrophotometry, high-performance liquid chromatography (HPLC), and gas chromatography (GC).

A recent paper introduced a compressed fluid-based separation process that combines carbon dioxide and ethanol to isolate portisins previously hemi-synthesized from blueberry surplus anthocyanins. The performance of the two-step separation process was compared favorably to centrifugal partitional chromatography (CPC) and conventional reversed-phase liquid chromatography (RPLC) findings that were reported in terms of portisins content in the extract, process throughput, process efficiency, and total solvent used.

Researchers investigated the use of electric field in dried blood spot (DBS) sample preparation for the detection of steroids in newborns using liquid chromatography-tandem mass spectrometry (LC-MS/MS) using both regular electroporation cuvettes and a custom vial setup.