John Chasse

LCGC spoke with key opinion leaders on the cutting edge of analytical science (both from academia and the private sector) to gauge the evolution of a variety of techniques and the opportunities this evolution will present.

Researchers have utilized ultra-high performance liquid chromatography-tandem mass spectrometry (UH PLC-MS/MS) to monitor 5-Fluorouracil, a medication used to treat various cancers, in dried blood spots. This process offers a simpler, more efficient method than those in place involving the monitoring of plasma.

A report estimates that the market for chromatography software will grow at an 8.92% CAGR between 2023 and 2033.

A report estimates that the market for high performance liquid chromatography equipment will grow at a 4.61% CAGR between 2023 and 2033.

Richard Bade of the Queensland Alliance for Environmental Health Sciences (QAEHS) within The University of Queensland (Australia) and colleagues have recently published a paper outlining the development and application of a new workflow utilizing the open-source platform InSpectra, aiming to complement targeted analysis and identify geographical spatial trends in wastewater samples across multiple countries. Bade spoke to LCGC International about their research paper and the work that inspired it.

In this interview to commemorate Earth Day, Ana Torres-Agullo and Silvia Lacorte share the results of using Pyr-GC-Orbitrap-MS to simultaneously determine the presence of 10 polymers in the air.

This two-part session focused on metabolomics and lipidomics, to better understand the science of cellular biology.

Scientists at the Analytica conference in Munich, Germany, spoke about clinical mass spectrometry and its use in metabolomics and lipidomics.

In this interview, Kevin Schug discusses his work using untargeted analysis and differentiation of psilocybin mushroom strains.

At the 2024 Pittcon Conference, Elizabeth Humston-Fulmer of LECO Corporation presented an improved workflow which uses two-dimensional gas chromatography (GCxGC) with dual time of flight (TOF) MS/FID detection. Shortly after Pittcon, Humston-Fulmer discussed this analytical method with us.

At the conference in San Diego, experts presented on a variety of trends in mass spectrometry for pharmaceuticals.

This year's awards were presented to Martina Catani and Wolfgang Lindner.

These lectures focused on method development and applications of mass spectrometry for bioanalytical, natural product, and agricultural studies.

The Dal Nogare Award is presented yearly to an outstanding scientist in the field of chromatography.

The award recognizes outstanding contributions to the field of separation science by a young chemist or chemical engineer from academia, industry, or national laboratories.

The AES Mid-Career Award recognizes exceptional contributions to the field of electrophoresis, microfluidics, and related areas by an individual who is currently in the middle of their career. This year’s recipient, Robbyn K. Anand, Suresh Faculty Fellow and Carlyle G. Caldwell Endowed Chair in Chemistry at Iowa State University, has, along with her group, developed methods for circulating tumor cell analysis, electrokinetic enrichment and separation of chemical species within water-in-oil droplets, and more sensitive bioanalysis at arrays of wireless bipolar electrodes (1).

Five prior winners of our annual Emerging Leader Award give their perspectives on how to thrive and find success in the separation science field.

At Pittcon 2023, LCGC spoke with Peter Schoenmakers of the University of Amsterdam, who is the winner of our 2023 Lifetime Achievement in Chromatography Award. This segment previews one of three Pittcon interviews that were conducted at the conference.

At Pittcon 2023, LCGC spoke with Emanuela Gionfriddo of the University of Toledo, who is the winner of our 2023 Emerging Leader in Chromatography Award. This segment previews one of three Pittcon interviews that were conducted at the conference.

At Pittcon 2023, LCGC spoke with Jim Grinias of Rowan University. This segment previews one of three Pittcon interviews that were conducted at the conference.

Top-down mass spectrometry (TD-MS) of peptides and proteins results in product ions that can be correlated to the polypeptide sequence. Joseph Loo and colleagues at the University of California-Los Angeles (UCLA) have developed ClipMS, an algorithm assigning both terminal and internal fragments generated by TD-MS fragmentation, which can be used to locate various modifications on the protein sequence.

Glen Jackson, Professor of Forensic and Investigative Science at West Virginia University, presented an "Expert Algorithm for Substance Identification (EASI): A New Paradigm for Mass Spectral Identifications" at SciX 2021, where it earned the FACSS Innovations Award. These awards are given for the most innovative and outstanding new research advancements debuted orally at the SciX Conference. Jackson spoke to Current Trends in Mass Spectrometry about his presentation.

Rebecca Gowland and her colleagues in the Department of Archaeology at Durham University in the United Kingdom have tested, for the first time, the applicability of a new method of sex estimation utilizing enamel peptides from a sample of permanent and deciduous teeth at different stages of mineralization, from nonadults of unknown sex, including perinates, and using a minimally destructive acid etching procedure and subsequent nano liquid chromatography– tandem mass spectrometry. She spoke to us about her efforts.

A preview of this year’s ASMS conference, in its new online format.

This Wednesday morning session begins at 9:00 am with Leonard Sidisky, Jamie Desorcle, Greg Baney, and Kathy Kiefer of MilliporeSigma presenting “Latest Developments in Ionic Liquid Stationary Phase Technology.”

This afternoon session begins at 1:30 p.m. with a keynote lecture titled “In-vivo SPME with Matrix Compatible Coatings Coupled to LC–MS and Directly to MS,” presented by Janusz Pawliszyn of the University of Waterloo (Waterloo, Canada).