January 2024

Panoramic skyline liverpool UK | Image Credit: © SakhanPhotography - stock.adobe.com

The Column interviewed Tony Edge, President of ChromSoc and Chair of the ISC Permanent Scientific Committee, to find out what participants can expect from the world’s oldest dedicated chromatography conference, being held this year in Liverpool, UK.

This month we interview Shijia Tang, principal scientist at Genentech, South San Francisco, CA, USA, about her innovative research focusing on the analysis of polymers and nanomaterials used in pharmaceutical analysis. Shijia decribes the benefits of an innovative in-line mixing modulation method for 2D-LC she developed for polymer and oligonucleotide analysis. The advantages of SEC–MALS to explore aggregation mechanisms for therapeutic constrained peptides and mRNA-lipid nanoparticles and their aggregates are also discussed.

Technological limitations have made it difficult for scientists to identify oligonucleotide aggregates. This can pose challenges when finding techniques to reliably analyze size variants for large nucleic acids and lipid nanoparticles (LNPs).

Clockwise from top left: David McCalley, Fabrice Gritti, John Langley, Kevin Schug, and Lucie Nováková | Image Credit: © ChromSoc

The UK-based Chromatographic Society (ChromSoc) has announced its two 2024 recipients of its most prestigious honor, the Martin Medal, in addition to three professors who have been chosen for the organization’s Silver Jubilee Medal.