June 2023 | LCGC North America

What Are Options to Improve My Separation? Part IV: Solutions to Consider for Improving Separation Speed

June 02, 2023

Column: LC Troubleshooting

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Several factors strongly influence separation speed, including the pressure available to drive the separation, column temperature, particle size, and column length. Developing efficient methods to improve speed while not sacrificing accuracy require an understanding of the abovementioned variables and analysis time.

Pharmaceutical Regulations: An Overview for the Analytical Chemist

June 02, 2023

Column: Perspectives in Modern HPLC

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What you need to know about pharmaceutical regulations as an analytical chemist is provided here, including an explanation about how working in a Good Manufacturing Practice (GMP) environment can yield positive results.

Analysis of Lipid Nanoparticles

June 02, 2023

Column: Focus on Biopharmaceutical Analysis

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Characterizing lipid nanoparticles (LNPs) is a developing delivery modality in biotherapeutic analysis. We address some of the current challenges and opportunities in this field, including an examination of the most common tools used to characterize LNPs.

A Standardized 2D-LC Screening Platform for Peak Purity Determination in Pharmaceutical Analysis

June 01, 2023

Peer-Reviewed Article

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This study suggests a 2D-LC screening method to evaluate peak purity and ensure specificity in pharmaceutical analysis, thereby promoting the safe production of medicines by detecting active pharmaceutical ingredients (API) and related substances.