Identifying Post-Translational Modifications in Monoclonal Antibodies Analyzing post-translational modifications-such as glycosylation, oxidation,
and deamidation-at different levels can reveal different types of information.
This is an exciting time for 2D-LC, as the expanding community of users works to develop creative solutions involving 2D-LC to solve analytical challenges that are very difficult or impossible to solve by conventional means.
With a simple liquid extraction approach and a short, 13-min GC method, dried blood spots can be analyzed effectively and rapidly. This method demonstrates that dried blood spot cards are an effective technique for toxicological studies.