September 2022 | LCGC North America

Chemistry in a Bottle: Ester Formation in Acidified Mobile-Phase Solvents

September 01, 2022

Column: LC Troubleshooting

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When esterification occurs in your LC mobile phase, knowing how baseline quality, retention, and selectivity are affected will help you mitigate the effects.

Highlights from the 50th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2022)

September 01, 2022

Column: Column Watch

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At HPLC 2022, we heard about new research and developments, in areas such as column technologies, portable instrumentation, and machine learning, among others.

Testing the Fundamentals: An Examination of Your Extraction Knowledge

September 01, 2022

Column: Sample Prep Perspectives

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Can you pass this test of chromatographic sample preparation concepts?

Getting “Under the Hood” of Gas Chromatography: Lessons from ChromTalks 2022

September 01, 2022

Column: GC Connections

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We pass on valuable lessons shared by the six GC speakers at ChromTalks 2022.

Analysis of Near 400 Pesticides in Tea via LC–MS/MS: Simple Sample Preparation and APCI to Improve Analyte Coverage

September 01, 2022

Columns

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This method greatly facilitates the analysis of a large number of pesticides.

Working with Data Scientists to Improve Online Chemical Extraction and Analysis

September 01, 2022

Columns

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We analytical chemists have a lot to gain by applying machine learning to our field—such as by using it to efficiently reach optimal conditions for challenging separations.

Nontargeted Screening for the Verification of Allergenic Ingredients and Perfume Authenticity by GC-ecTOF-MS

September 01, 2022

Peer-Reviewed Article

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In this study, the experimental nontargeted screening approach and corresponding data analysis workflows—simultaneously using molecular ion information and structural information—are presented for the molecular identification and authenticity verification process from a brand perfume using GC–ecTOF-MS.

Minimizing the Risk of Missing Critical Sample Information by Using Two-Dimensional Liquid Chromatography

September 01, 2022

Peer-Reviewed Article

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Online 2D-LC is a powerful—and accessible—tool for analyzing pharmaceutical and biopharmaceutical samples, in both R&D and QC. It’s now easier than ever to develop 2D-LC methods, and they can be run in a fully automated manner.