All News

Shimadzu?s new LCMS-8050 triple quadrupole LC-MS/MS meets the growing demand for trace-level quantitation in clinical research and other markets. It incorporates proprietary ultrafast technologies as well as a newly developed ion source and collision cell technology. As the flagship model of Shimadzu?s UFMS (Ultra-Fast Mass Spectrometry) product line, the LCMS-8050 features high sensitivity, high data quality and the world?s fastest data acquisition rates.

The Microlute SPE sample preparation system from Porvair Sciences provides a faster, trouble-free alternative to cartridges for high throughput sample clean-up. Handling samples as small as 150?l the Microlute? SPE sample preparation system helps you increase your assay sensitivity by providing pre-injection clean-up and concentration you can trust.

Thermo video application note: organic brown rice syrup analysis

Researchers coupling high performance liquid chromatography to mass spectrometry face the challenge of segregating the ionized, typically nonvolatile analytes from a large amount of solvent, and the mobile phase is an important component in the process. LCGC Blog editor Kevin Schug discusses factors to consider when choosing a mobile phase for LC-MS.

Kevin A. Schug, professor at the University of Texas, Arlington (Texas, USA) and LCGC North America EAB member, has led a team to survey and assess the impact of natural gas extraction from shale, also known as "fracking", on nearby water sources. The results of the assessment were recently published in the journal Environmental Science & Technology.1

Choosing proper tubing connections throughout the entire system, especially when capillary tubing is used, can dramatically improve the level of sensitivity and quality of data obtained with most LC–MS systems.

A German/Chinese team led by Rainer Lehmann, of the University of Tuebingen (Tuebingen, Germany) and Guowang Xu, of the DICP (Dalian, China), has developed a method of simultaneously extracting metabolites and lipids using methyl tert-butyl ether (MTBE) from single small tissue samples for analysis by ultrahigh-pressure liquid chromatography–mass spectrometry (UHPLC?MS).

Click here to view the full LCGC Europe E-newsletter from 5 September.

Metrohm launches the 940 Professional IC Vario, the new high-performance ion chromatography system for research applications and routine use. The 940 Professional IC Vairo is Metrohm?s most versatile IC system yet.

Alan Rawle, Divisional Applications Manager at Malvern Instruments (Malvern, UK), has been accepted as a Fellow of the Royal Society of Chemistry (FRSC).

Emmanuel Barillot, Director of Bioinformatics and Systems IT at the Institut Curie (Paris, France), has received an Agilent Thought Leader Award. Agilent will contribute financial support, products, and expertise to the work by Barillot to develop a database of cellular signalling pathways and a visualization tool to help the pharmaceutical industry develop more effective cancer treatments. The web-based tool will enable the identification of off-pathway effects of new drugs.

Shimadzu Europa GmbH

PSS Polymer Standards Service GmbH

Metrohm

Tosoh Bioscience

Malvern Instruments Ltd.

Wyatt Technology Corporation

Biotage LLC

Toxicology Laboratory at the Veterans Administration, Portland, Oregon, USA, Agilent Technologies

Wyatt Technology Corporation

Bruker Daltonics

Click the title above to open the LCGC Europe September 2013 Applications Book, Vol 26 No s9, in an interactive PDF format.

The 40th International Symposium on High Performance Liquid Chromatography and Related Techniques (HPLC2013-Hobart) will take place at the Hotel Grand Chancellor, Hobart, Tasmania, Australia, from 18–21 November 2013.

A review of the trends at this year's symposium, including discussions of column technology, sample preparation, and detector usage.

How do you identify the cause of unstable retention times?

In this instalment, a way of utilizing HR-MS systems to characterize the structures of metabolites is introduced. This results in a general workflow for metabolism studies for drug discovery and development.

Green Foodomics

Secrets to Successfully Translating and Transferring HPLC Methods