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Dolan addresses the problems associated with transfering a validated method from one laboratory to another and considers what changes are permissable.

The use of SLM extraction in speciation studies is discussed, especially for determining the form and bioavailable fractions of metals in enviromental and biological matrices.

The authors discuss zero-, first- and second-order data and describe the advantages of using second-order chromatographic data compared with the more traditional univariate or multivariate calibration. They demonstrate how its use can uncover much more information from chromatograms and spectra.

The authors consider the impact an analytical balance can have on the quality of chromatographic analyses.

A look back at the life of this chromatography pioneer.

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Dionex Corporation. For more information, visit the company's website at www.dionex.com.