All News

Hinshaw provides an overview of scientific presentations and technology developments from the 26th International Symposium on Capillary Chromatography and Electrophoresis.

Majors discusses highlights from HPLC 2003, held June 2003 in Nice, France.

This column discusses the beginnings of GC in the United States and four early symposia.

Dolan responds to reader comments and questions in celebration of the 20th anniversary of "LC Troubleshooting."

John Dolan discusses the causes of peak tailing, how to measure it, preventive measures, and why newer column types are less prone to tailing problems.

This column is the first installment in a two-part series reviewing ICH and FDA impurity method validation guidelines.

This article focuses on the initial development of an LC–MS method to screen for cyanotoxins at low parts-per-billion levels.

John Hinshaw writes about the role that the American Society for Testing and Materials International plays in chromatography standardization.

The guest authors describe capillary columns for ultrahigh pressure liquid chromatography.

The guest authors discuss current procedures for protein sample preparation, protein analysis, and automation.

This month's column addresses problems submitted by readers, including negative peaks, pressure increases, and peak-width increases.

Dolan examines the causes of LC system leaks and suggests some preventive maintenance to minimize their occurrence.

The guest authors describe sample preparation techniques based on liquid membrane extraction.

Leslie Ettre discusses the life and activities of the inventor of chromatography.

The authors test and compare performance of three types of LC–MS systems for precision, linearity, selectivity, accuracy, and sensitivity in the quantitation of drug impurities.

The authors describe GC product introductions at Pittcon 2003.

The authors discuss the advantages and disadvantages of evaporative light-scattering detection and chemiluminescent nitrogen detection for determining compounds lacking UV chromophores.

The conclusion of a two-part series in which Ron Majors examines the trends in column introduction at Pittcon 2003.

This article presents an organic solvent–free method for the determination of oxytetracycline residue in cow's milk using HPLC.

The author reports a comparative study of the interaction of aromatic amino acids with a class of highly sulfated cyclodextrins as the chiral selectors by capillary electrophoresis.

John Hinshaw examines the tools and accessories that gas chromatographers use in their laboratories.

Flow-rate changes might or might not be acceptable means to adjust retention.

This article reviews several common applications of the critical-pair approach to column chromatography as it is applied under pharmaceutical guidelines and validation strategies.

John Hinshaw examines the effects of system time constants and sampling rates on apparent peak shapes and areas.

The first of two columns about new chromatography columns, accessories, and sample preparation products introduced at Pittcon 2003.

John Dolan provides 10 tips for the proper care and use of LC columns.

This column explores and highlights recently published guidelines for bioanalytical method validation.

The authors compare thermally tuned tandem column separations with single-column optimization strategies.