Mass Spectrometry

A new method for monitoring tricyclic antidepressants (TCA) in biological fluids and tissues in real time was proposed for the purposes of improving their effects or determining causes of death.

In a talk at ASMS 2023, Rebecca L. Beres of the University of North Carolina at Chapel Hill focused on two types of analysis methods: liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) and a liquid chromatography, ion mobility spectrometry, and mass spectrometry (LC–IMS-MS) platform.

An oral session recognizing the John B. Fenn Distinguished Contribution in Mass Spectrometry Award winner and the Al Yergey MS Scientist Award winners took place on Monday, June 5th, from 4:45–5:30 pm.

Speaking at ASMS 2023, Sara Schlange of the University of Nebraska-Lincoln discussed a mass spectrometry (MS)-based alternative for matrices problematic in current immunoassays regarding the detection of peanut allergens.

At ASMS 2023, LCGC spoke with Erin Baker of the University of North Carolina at Chapel Hill. This segment previews one of several ASMS interviews that were conducted at the conference.

At ASMS 2023, Bayan Almasri of the University of Lille proposed a combination of techniques for the deciphering of insoluble polyester polymer structure.

Characterizing lipid nanoparticles (LNPs) is a developing delivery modality in biotherapeutic analysis. We address some of the current challenges and opportunities in this field, including an examination of the most common tools used to characterize LNPs.

This study suggests a 2D-LC screening method to evaluate peak purity and ensure specificity in pharmaceutical analysis, thereby promoting the safe production of medicines by detecting active pharmaceutical ingredients (API) and related substances.

The latest developments and challenges of using liquid chromatography (LC) for copolymer analysis are discussed.

Here, we preview the 16 Wednesday evening workshops that will take place from 5:45–7:00 pm at ASMS.

Today from 2:30–4:30 pm, an oral session on non-targeted analysis and emerging environmental contaminants will take place. We preview this session here.

ASMS 2023 is excited to be hosting its annual conference in Houston, Texas. Here is what to expect on Sunday evening.

We offer a sneak peek at some of the award presentations that will be taking place at the ASMS 2023 Conference this week.

ASMS will conclude its conference at the Houston Museum of Natural Science (HMNS) on Thursday June 8th, from 7:00 to 10:00 pm. The HMNS is known for their paleontology display, giving attendees the opportunity to embark on a one-of-a-kind prehistoric journey while socializing with friends and colleagues.

The upcoming 2023 ASMS Conference will feature two concurrent tutorial sessions on Sunday, June 4, from 5:00–5:45 pm, along with a Special Keynote Section from 5:45–6:30 pm that will feature local activists from the Houston community.

A novel system combining hydrogel-modified human umbilical vein endothelial cell membrane chromatography with high-performance liquid chromatography-mass spectrometry revolutionizes the screening and purification of active ingredients in herbal medicines.

A new publication introduces a groundbreaking automated system for high-throughput mass spectrometry analysis, reshaping the future of biotherapeutic characterization.

A new approach was sought for the simultaneous verification of carboxyl and aldehyde metabolites, including analytes that were previously undetectable.

A recent study has introduced comprehensive quality control procedures for large-scale plasma proteomics analyses. The research provides valuable insights into optimizing performance, enhancing reproducibility, and ensuring quantitative accuracy in proteomics investigations.

A novel analytical method combines charge inversion ion-ion reactions with ion mobility–mass spectrometry to enhance the separation and characterization of oligosaccharides.

A new tandem mass spectrometry technique has been developed for the rapid determination of complex lipid A structures, including novel variations from arctic bacterioplankton. This study enhances our understanding of bacterial adaptations and paves the way for the development of targeted therapies and antimicrobial agents.

Using intact protein separation (IPS) together with traditional peptide separation (PS) enhanced detection for LC–MS/MS better than either method could do independently.

Extraction of gasoline and its major aromatic groups was promising using a carbon nanotube-assisted solid-phase microextraction (CNT-SPME) fiber.

A cutting-edge technique combining droplet microfluidics and mass spectrometry revolutionizes monoclonal antibody screening, enabling rapid and high-throughput analysis while setting a new standard for efficient clone selection in biopharmaceutical development.

Automation and high-throughput MALDI mass spectrometry revolutionize peptide metabolic stability screening, allowing for rapid analysis of a large number of samples and minimizing solvent waste.