Mass Spectrometry

A pioneer of FT-ICR Mass Spectrometry, Alan G. Marshall (1944–2025), is best known for co-inventing Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), a transformative technique that enabled ultrahigh-resolution analysis of complex mixtures. Over a career spanning more than five decades at institutions like the University of British Columbia, The Ohio State University, and Florida State University, he published over 650 peer-reviewed papers and mentored more than 150 scientists. Marshall’s work profoundly impacted fields ranging from astrobiology to petroleomics and earned him numerous prestigious awards and fellowships. Revered for his intellect, mentorship, and dedication to science, he leaves behind a legacy that continues to shape modern mass spectrometry.

Monitoring the quality of essential oils is vital for protecting consumer health. Researchers recently combined gas chromatography and mass spectrometry approaches to gather data on mandarin essential oils.

As a precursor to the Lindau Nobel Laureate Meetings, Texas A&M University held a meeting for future Lindau attendees to highlight the institution’s scientific facilities. One such attendee is Caitlin Cain of the University of Michigan, one of LCGC International’s 2024 Rising Stars of Separation Science.

In the food industry, evolving consumer demands, contamination concerns, and workforce issues are driving significant changes in food analysis and instrumentation.

Here is some of the most-read content posted on LCGC International this week.

Grape pomace, a byproduct of the winery industry, holds various phenolic compounds within it. Scientists used liquid chromatography-based techniques to harvest these potentially beneficial components.

New QuEChERs-based methods were created to detect pesticide residues in commercial dry pet food.

Shea kernels contain bioactive secondary metabolites that can offer potential health benefits. Researchers aimed to learn more about these substances.

At the 2025 ASMS conference, YongDong Wang, co-founder and CEO of Cerno, emphasized the critical importance of high-quality, calibrated data as the foundation for effective AI and machine learning applications in mass spectrometry, while advising young chemists to master fundamentals alongside emerging technologies.

Here is some of the most popular content posted on LCGC International this week.

At the ASMS Conference in Baltimore, the company highlighted several new products tailored to a range of application areas, including biopharmaceutical development and environmental analysis.

Cerno Bioscience develops vendor-neutral software to streamline mass spectrometry spectral analysis, partnering with major manufacturers like Agilent and Thermo Fisher Scientific while expanding into new global markets.

Webinar Date/Time: Thu, Jun 26, 2025 11:00 AM EDT

At this year’s ASMS conference, LCGC interviewed executives from leading analytical science and technology companies to explore emerging trends and gain professional insights. During these discussions, they focused on key advice for early-career analytical chemists to prioritize in today’s evolving field.

This review highlights the high performance liquid chromatography (HPLC), mass spectrometry (MS), chromatography data systems (CDS), and related products that were introduced from 2024 to 2025, summarizing the technical specifications of each product and highlighting significant user benefits.

At the ASMS 2025 conference, Sciex showcased its latest mass spectrometry system, the ZenoTOF 8600, along with updates to its software platform designed to enhance data processing and analysis for complex workflows.

Water pollution management is an important process that faces difficulty with handling microplastics. University of Porto (Portugal) researchers aimed to optimize existing methods to help rectify this issue.

Thermo Fisher Scientific launched two advanced mass spectrometers and emphasized its multi-omics strategy during the American Society for Mass Spectrometry (ASMS) conference in Baltimore, Maryland this week.

At the ASMS conference, Jack Henion emphasized contributions from colleagues and industry partners. He reflected on innovations that have shaped liquid chromatography–mass spectrometry (LC–MS) and the importance of teamwork in driving scientific breakthroughs.

Jonah Kirkwood, Agilent’s chief commercial officer, emphasized the company’s focus on high-growth markets and its dedication to partnering closely with customers to address their changing needs.

Here is some of the most popular content posted on LCGC International this week.

In a new study, researchers explored quantifying bile acids and tryptophan metabolites in human serum samples was created using ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC–MS/MS).

To address multi-drug resistance (MDR) among harmful substances, liquid chromatography–tandem mass spectrometry was used to test fosfomycin as a means of bypassing growing MDR amongst microorganisms.

Diflubenzuron and similar compounds can be signs of cattle fever ticks, which can cause morbidity in cattle. LC–MS/MS was recently tested as a means of detecting these disease-carrying insects.

Detecting tryptophan and other metabolites can be done using various techniques. Researchers created a new UHPLC–MS/MS-based method for quantifying these substances in human plasma.

While venous blood sampling can help gain understanding of patients’ health through phenolic compound analysis, this process can prove discomforting. Volumetric absorptive microsampling has recently been proposed as a more suitable and equally effective alternative.