In this episode, Carrie McDonough, assistant professor of chemistry at Carnegie Mellon University, explores the unique analytical challenges posed by short-chain PFAS, highlighting issues with detection sensitivity, separation difficulties, and the promising role of emerging techniques like ion mobility in improving analytical performance.
To watch the full series of videos from this peer exchange, visit the main event page here.
Analytical Challenges in Measuring Migration from Food Contact Materials
November 2nd 2015Food contact materials contain low molecular weight additives and processing aids which can migrate into foods leading to trace levels of contamination. Food safety is ensured through regulations, comprising compositional controls and migration limits, which present a significant analytical challenge to the food industry to ensure compliance and demonstrate due diligence. Of the various analytical approaches, LC-MS/MS has proved to be an essential tool in monitoring migration of target compounds into foods, and more sophisticated approaches such as LC-high resolution MS (Orbitrap) are being increasingly used for untargeted analysis to monitor non-intentionally added substances. This podcast will provide an overview to this area, illustrated with various applications showing current approaches being employed.