Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates Using a TSKgel Super SW3000 Size-Exclusion Column

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Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates Using a TSKgel Super SW3000 Size-Exclusion Column

Published on: August 1, 2002

LCGC North America

LCGC North America, LCGC North America-08-01-2002, Volume 20, Issue 8

Replacing sodium chloride with sodium perchlorate in the separation of an antibody-based fusion protein provided the robustness of an otherwise problematic separation method. (Tosoh Biosep LLC)