Application Notes: LC

Cannabinoid Separations and the Impact of LC Column Selectivity

November 30, 2022

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The natural products of the cannabis plant can number up to 100, but the scientific community is concerned with a smaller portion of around 10 to 20 compounds.

LPH-C18: A C18 Column Alternative

November 30, 2022

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A low pH compatible, 90 Å, superficially porous particle C18 phase is introduced as an addition to the chromatographer’s toolbox.

Separation of 18 Cannabinoids Using HALO LPH-C18

November 30, 2022

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A HALO® LPH-C18 column is used to separate a mixture of 18 cannabinoids, showing fast results and high resolution within critical pairs.

Vitamin E(xtraordinary), Isolation of Tocopherols by PRP-1 (Nov 2022)

November 15, 2022

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The fast identification of tocopherols is important for various applications including free radical scavenging for human health and food stuff preservation.

Analysis of mRNA Coupled to EGFP

November 08, 2022

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mRNA coupled to EGFP (enhanced green fluorescent protein) is analyzed using a widepore YMC-Accura Triart Bio C4 RP column as well as a non-porous BioPro IEX QF column.

Systematic Reversed-Phase method development

October 20, 2022

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Explore how a systematic screening strategy allows chromatographers to rapidly identify ideal method conditions.

Application of Solid-Core Particles

October 20, 2022

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This white paper explores the theory behind solid-core particles and the advantages they offer for small molecule analysis.

Importance of Column Temperature in LC

October 20, 2022

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This article discusses the impact and theory of column temperature and how it can be a powerful tool for fine-tuning a separation during method development.

Increase Throughput with Rapid LC–MS/MS Separations

October 20, 2022

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An increased number of samples demands increased throughput. This article discusses ways to achieve high throughput analysis with LC–MS analysis methods.

Mobile Phase pH for Method Development

October 20, 2022

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In LC separations, the majority of analytes are ionizable, so controlling the state the analytes are in is critical. Discover how to harness pH for method development.