Application Notes: LC

This application note demonstrates the potential of valorizing mother liquor using Centrifugal Partition Chromatography (CPC) to remediate minor cannabinoids.

This application note discusses the latest development on high performance cation exchange bio-separation columns for determining charge variants in protein-based biotherapeutics, as well as the strategy on method development.

In this application note the chelating agents 8-hydroxyquinoline and hinokitiol were analyzed using a bioinert coated YMC-Accura Triart C18 column.

Experience high recoveries from the first injection! YMC Accura BioPro IEX SF columns provide excellent peak shapes for the ion-exchange analysis of mAbs.

Discover the supremacy of the bioinert coated hardware of YMC Accura BioPro IEX QF columns for reproducible analysis of oligonucleotides in ion-exchange chromatography.

A new technical study demonstrates the utility of a non-invasive liquid flowmeter for validating the performance of HPLC systems across a range of 9 different solvents.

We assess the benefits of the Alliance iS Bio HPLC System by migrating and modernizing a compendial SEC method outlined in the USP General Chapter <129>.

Combining the gradient method adjustments with the Alliance™ iS HPLC System to achieve both column dimension and system modernization for the USP monograph separation of abacavir sulfate

We show the development of HPLC-ELSD methods for high-throughput and sensitive analysis of the lipids in lipid nanoparticles (LNPs), used to administer mRNA vaccines.

This brief communication highlights the assessment of Hamilton PRP-3 HPLC column attributes when analyzing biologically active peptides.

Despite the utility of the essential oil mixture, it has been shown that allergies can arise from some of the individual components.

Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions.

Chromium can pose as a beneficial element or a poison, therefore it is imperative to identify contaminated waters, especially drinking water.

GRPC peptides are found in the entire body. Isolation of seven classic GRPC peptides initiating in the GI tract could implicate disease.

The isolation and identification of 5 common psychedelic compounds was performed using the alkaline ion-pairing agent hexylamine to facilitate excellent resolution.

This note summarizes the optimal methods for the HPLC separation of semaglutide and liraglutide under acidic and alkaline conditions.

Discover the supremacy of the bioinert coated hardware of YMC Accura BioPro IEX QF columns for reproducible analysis of oligonucleotides in ion-exchange chromatography.

We show the development of HPLC-ELSD methods for high-throughput and sensitive analysis of the lipids in lipid nanoparticles (LNPs), used to administer mRNA vaccines.

Recycling chromatography is a powerful technique that allows the separation of two closely eluting peaks by increasing the column bed length.

KNAUER AZURA UHPLC system, thanks to the low dispersion and operating pressure up to 1240 bar, allows to speed up your method and increase throughput preserving resolution

Trifluoroacetic acid (TFA) as an eluent modifier causes baseline ripples, with negative effect on LOD/LOQ. This can be mitigated by adjusting the pump mixer volume

The KNAUER HPLC Method Converter assists you to modernize the analytical method according to the allowed variations last US and EU Pharmacopeia (USP) chapter 621

A preparative system setup is presented for the purification and fractionation of target substances at flow rates up to 800 ml/min with a max. back pressure of up to 100 bar.

Successful large-scale ion exchange chromatography purification of oligonucleotides provided by BianoGMP GmbH, experts in the productions of therapeutic oligonucleotides

This application notes showcases greener HPLC with less solvent using smaller inner diameter columns while maintaining the quality of separation

This application notes showcases greener HPLC with less solvent using smaller inner diameter columns while maintaining the quality of separation

This application notes showcases greener HPLC with less solvent using columns of shorter length and smaller inner diameter while maintaining the quality of separation

This application notes showcases greener HPLC with less solvent using columns of shorter length and smaller inner diameter while maintaining the quality of separation