Application Notes: LC

This application note covers high-resolution oligonucleotide analysis using FlexFire’s new Wide Pore (WP) C18 1.6 µm column.

YMC-Triart Bio C4 is used to successfully analyze monoclonal antibodies in reversed-phase mode in this robust application.

This application note demonstrates the use of YMC-Triart C18 ExRS for UHPLC potency analysis of 11 common cannabinoid compounds.

This application note explores when to use each of YMC’s two HIC columns by comparing retention behaviors of BioPro HIC HT and BioPro HIC BF.

FFF combined with NTA can be used in the development of therapeutics for biological samples for the optimization process in clinical trials under in vivo conditions.

This brief communication highlights the assessment of Hamilton PRP-3 HPLC column attributes when analyzing biologically active peptides.

This case study demonstrates how method modernization is less difficult than the common perception, and good practices can be put in place to streamline the process.  

Analyzing crops for beneficial and harmful compounds is an indispensable tool for assessing the viability of various agricultural crops for consumption.

This application note covers oligonucleotide analysis using FlexFire’s new Wide Pore (WP) C18 1.6 µm column.

This application note demonstrates the performance of the miniLC LC–UV analyzer for the analysis of catechins and epicatechins in teas.

This app note shows how CPC can produce a high-quality standard of [6]-gingerol without the use of silica-based chromatography methods, such as FLASH and prep HPLC.

A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs.

We examined FlexFire columns and their analytical conditions using the synthesized miRNA samples. For this study, we applied inert UHPLC columns to prevent sample loss.

This application details how the FlexFire mAb-RP column allows for accurate analysis of a wide range of molecular sizes.

Large viral vectors are characterized rapidly using dynamic light scattering and in-depth by multi-angle light scattering in combination with field-flow fractionation.

This bibliography is a guide to the scope of Vanquish HPLC and UHPLC usage in literature. Publications have been categorized based on either target analyte or field of application.

This compendium features proven techniques to help tackle common instrument challenges faced during method transfers to obtain consistent results and sustain regulatory compliance.

This application note demonstrates the performance of the SCION LC6000 HPLC for the analysis of cannabis potency.

This application note introduces a sensitive simultaneous analysis method for lactose, allolactose, lactulose, and, six other saccharides.

The fast identification of tocopherols is important for various applications, including free radical scavenging for human health and food-stuff preservation.

IEX-MALS overcomes some of the restrictions of SEC-MALS that arise from SEC, while providing absolute molar mass, size, and quality assessment of heterogeneous proteins.

Accelerate deconvolution of complex MS samples with software that generates an extensive, unbiased, relevant list of structures and component identifiers for your data.

This application note demonstrates a streamlined HPLC method scouting workflow for the analysis of esomeprazole and related degradation products.

A YMC-Triart C18 and a YMC-Triart SIL column were used in RP and NP mode, respectively, for the analysis of four different phosphoramidites.

The recently introduced 1 mm YMC-Triart C18 UHPLC column was used for the high sensitivity LC–MS screening of six antineoplastic drugs.

A YMC-Triart C18 and a YMC-Triart SIL column were used in RP and NP mode, respectively, for the analysis of four different phosphoramidites.

Mipomersen was analyzed by LC–HRMS using a biocompatible YMC-Triart C8 metal-free column, ensuring symmetric peaks, high sensitivity, and no carryover effects.