Application Notes: LC

Excellent separation and chemical stability in oligonucleotide isolation is observed. The C18 column provides loading capacities and reliability needed for repeat use.

Identification of the five most common saccharides found in packaged foods, lactose, maltose, sucrose, fructose, and glucose, is easily resolved on the RCX-30 column.

GRPC peptides are found in the entire body. Isolation of seven classic GRPC peptides initiating in the GI tract could implicate disease.

Hydrophilic Interaction Liquid Chromatography (HILIC) can provide better separation for oligosaccharide analysis than Size Exclusion Chromatography (SEC) mode does.

This application demonstrated the effectiveness of Shodex™ HILICpak™ VG-50 4E with its HILIC mode for the analysis of various sugars found in Japanese sake.

mRNA coupled to EGFP (enhanced green fluorescent protein) is analyzed using a widepore YMC-Accura Triart Bio C4 RP column as well as a non-porous BioPro IEX QF column.

Different oligonucleotide mixtures were analyzed using the bioinert coated column YMC-Accura Triart Diol-HILIC in comparison to the conventional stainless steel column.

Four phosphopeptides are analyzed using a bioinert coated YMC-Accura Triart C18 column. The column provides high intensities, recoveries, and great peak shapes.

This application note demonstrates improved performance when separating polar compounds using Agilent's InfinityLab Poroshell 120 Aq-C18 column

Four phosphopeptides are analyzed using a bioinert coated YMC-Accura Triart C18 column, providing high intensities, recoveries, and great peak shapes.

This application note describes online monitoring of a chemical reaction that produces a byproduct, and presents a fully automated sampling workflow.

Learn how a single method was developed for simultaneous determination of two active ingredients, replacing several separate methods for the analysis of assays and organic impurities.

Find out how the Alliance iS HPLC System makes method migration more straightforward with usability features that limit analyst error and improve system reliability.

Pharma QC labs face growing demands to do more with less. With capabilities developed specifically for the QC lab, the Alliance iS HPLC System will quickly become your favorite ally.

Learn how to generate quality data that meets the regulatory requirements of the U.S. Pharmacopeia Chapter <621> with the Alliance iS HPLC System.

See how the Alliance iS HPLC System’s tool-free fittings and improved wash function can eliminate volumetric carryover and reduce adsorptive carryover, respectively.

Peptide analysis in the GI tract shows links to endocrine, cardiac, and nervous systems. See how Hamilton Company isolates GPCR binding peptides with its PRP-3 column.

Find out how the Alliance iS HPLC System makes method migration more straightforward with usability features that limit analyst error and improve system reliability.

See how the Alliance iS HPLC System’s tool-free fittings and improved wash function can eliminate volumetric carryover and reduce adsorptive carryover, respectively.

This application shows how Shodex HILICpak columns can separate high-molecular weight oligosaccharides that proved difficult with preexisting HILIC columns.

This application shows howShodex HILICpak columns can separate high-molecular weight oligosaccharides that proved difficult with preexisting HILIC columns.

This application note shows how using the Shodex HILICpak VC-50 2D column with LC–MS provides highly sensitive analyses of various low molecular weight cationic compounds.

Triazines in water supplies cause endocrine disruption in reproduction of some animals. See how Hamilton's HPLC columns can separate seven federally approved triazines.

Analyzing crops for beneficial and harmful compounds is an indispensable tool for assessing the viability of various agricultural crops for consumption.

Honey has medicinal and healing properties, but it often contains refined sugars to extend supply. See how Hamilton's HC-75 column exposed Nevada honey adulteration.

This application note highlights the assessment of Hamilton PRP-3 HPLC column attributes when analyzing biologically active peptides.

This application note explains how Hamilton Company's PRP-C18 method offers a fast, simple solution for identifying vitamin K congeners.

This application note describes a method to confirm the seven most common flavonoids found in cannabis using the PRP-1 column.