MilliporeSigma

Articles by MilliporeSigma

This article will discuss several aspects of working with high purity water in LC-MS analyses including quality and handling. Solutions will be proposed for optimal water purification based on the use of complementary purification technologies combined with application-specific final filtering, and finally, the importance of water purification system maintenance will be discussed.

This article will discuss several aspects of working with high purity water in LC-MS analyses including quality and handling. Solutions will be proposed for optimal water purification based on the use of complementary purification technologies combined with application-specific final filtering, and finally, the importance of water purification system maintenance will be discussed.

Quantitative measurement of biotherapeutic and clinically important biomarker proteins using LC-MS/MS has seen great development in the last 15 years. Stable Isotope Labelled Internal Standards are a cornerstone of accurate quantitation and there are several options ranging from signature peptides to “winged” longer peptides or full 13C and/or 15N labelled proteins to choose from. In this video Kevin Ray, Kwasi Mawunyega and Anders Fridstrom will discuss pros and cons with different SIL IS approaches as well as similarities and differences between biopharmaceutical bioanalysis and biomarkers for disease research & diagnosis.

MilliporeSigma experts will be sharing their experience in providing tips for protein biologics sample preparation. Special focus is on reduction and deglycosylation for characterizing antibody-drug conjugates, as well as enzyme and chemical treatment options to ensure desired results when deglycosylating glycoprotein samples.

Biopharmaceutical Analysis Focus 2020: A Virtual Symposium

***Live Dates:Day 1, Wednesday, November 18, 2020 9am–11:30am EST | 2pm – 3:30pm GMT | 3pm-4:30pm CET Day 2, Thursday, November 19, 2020 9am–11:30am EST | 2pm – 3:30pm GMT | 3pm-4:30pm CET ***Biopharmaceutical analysis is a fast-paced and constantly evolving field, and chromatographers play a pivotal role. This two-day virtual event, focusing on cutting-edge trends, has been organized by The Chromatographic Society (“ChromSoc”) in collaboration with LCGC and features talks from top analytical chemists working in biopharmaceutical analysis.***On demand available after final airing until Nov. 19, 2021***

Applications of Field-Flow Fractionation in Drug Delivery Analysis

Are you using sample preparation techniques effectively in your HPLC and GC methods? Are you aware of the latest advances in sample preparation? Join us for this informative web seminar to learn more about how to use sample preparation effectively and the latest advances in sample preparation techniques. The panelists can answer your questions too! Part 1: Thursday, Sept. 17, 2020 at 10am EDT| 2pm BST| 3pm CEST Part 2: Friday, Sept. 18, 2020 at 10am EDT| 2pm BST| 3pm CEST On demand available after final airing until Sept. 18, 2021.