LCGC Europe-02-01-2015

Experimental results and method validation data from two analytical case studies of complex small?molecule pharmaceuticals illustrates the utility and advantages of UHPLC in high-resolution separations.

A rapid, high-throughput analytical method was developed and evaluated for the simultaneous determination of pesticides and environmental contaminants in fish.

Why are LC retention times sometimes so slow to stabilize?

HPLC 2015 - The 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques

The retention and selectivity of stationary phases in HILIC is discussed.

An excerpt from LCGC's e-learning tutorial on GC column selection at CHROMacademy.com

This instalment of “Questions of Quality” looks at problems with an operational liquid chromatograph to see if they can be picked up in the performance qualification (PQ) or prevented in the operational qualification (OQ).

Click the title above to open the LCGC Europe February 2015 regular issue, Vol 28, No 2, in an interactive PDF format.

Fluorescence-detection size-exclusion chromatography and its implications in protein characterization, specifically the development and characterization of biologics, is reviewed.