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LCGC Europe-12-01-2014
LCGC Europe
Liquid Chromatography Methods for the Separation of Short RNA Oligonucleotides
December 01, 2014
Features
27
12
Synthetic oligonucleotides have become increasingly popular as a result of the recent discovery of ribonucleic acid interference (RNAi), a natural process for silencing gene expression.
Assessing the Suitability of a Green Solvent for GPC and TREF Analyses of Polyethylene
December 01, 2014
Features
27
12
This study presents results of gel permeation chromatography (GPC) and analytical temperature rising elution fractionation (TREF) of polyethylene in butylal (dibutoxymethane, a halogen-free solvent).
Quantifying Small Molecules by Mass Spectrometry
December 01, 2014
27
12
The use of a mass spectrometer in quantitative analysis exploits its exquisite selectivity and sensitivity as a detector, allowing a signal to be ascribed to a particular chemical entity with high certainty, even when present in a sample at a low concentration. There are, however, some special considerations that are necessary when a mass spectrometer is used as a quantitative tool.
A Single-Method Approach for the Analysis of Volatile and Semivolatile Organic Compounds in Air Using Thermal Desorption Coupled with GC–MS
December 01, 2014
Cover Story
27
12
This article describes a new, single method to replace the two-method approach using United States EPA Methods TO-15 and TO-13A for the analysis of both VOCs and SVOCs in air.
Understanding and Improving Solid-Phase Extraction
December 01, 2014
Sample Preparation Perspectives
27
12
Vol 27 No 12 LCGC Europe December 2014 Regular Issue PDF
December 01, 2014
Issue PDF
27
12
Click the title above to open the LCGC Europe December 2014 regular issue, Vol 27, No 12, in an interactive PDF format.
The Role of Elution Gradient Shape in the Separation of Protein Therapeutics
November 30, 2014
Biotechnology Today
27
12
In this article, we discuss the role of the gradient in protein separations by reversed-phase and ionexchange high performance liquid chromatography (HPLC).
A Single-Method Approach for the Analysis of Volatile and Semivolatile Organic Compounds in Air Using Thermal Desoprtion Coupled with GC–MS
November 30, 2014
27
12
This study presents results of gel permeation chromatography (GPC) and analytical temperature rising elution fractionation (TREF) of polyethylene in butylal (dibutoxymethane, a halogen-free solvent).