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LCGC North America-06-01-2018
LCGC North America
Vol 36 No 6 LCGC North America June 2018 Regular Issue PDF
June 01, 2018
Issue PDF
36
6
Click the title above to open the LCGC North America June 2018 regular issue in an interactive PDF format.
The Promise of Metal–Organic Frameworks for Use in Liquid Chromatography
June 01, 2018
Column: Column Watch
36
6
What can metal–organic frameworks offer for liquid chromatography?
Peak Purity in Liquid Chromatography, Part III: Using Two-Dimensional Liquid Chromatography
June 01, 2018
Column: LC Troubleshooting
36
6
Here, we see how 2D-LC can solve coelution problems that are difficult or impossible to address using peak purity tools or curve resolution methods.
Perspectives and Characterization on Antibody–Drug Conjugates
June 01, 2018
Column: Perspectives in Modern HPLC
36
6
Comprehensive characterization of ADCs requires increasingly powerful approaches consisting of small- and large-molecule techniques.
Analytical Characterization of Biotherapeutic Products, Part I: Quality Attributes
June 01, 2018
Column: Focus on Biopharmaceutical Analysis
36
6
To ensure the reliable and accurate characterization of biotherapeutics, an arsenal of orthogonal analytical techniques is needed.
HPLC Troubleshooting: Autosampler Contamination
June 01, 2018
Column: The Essentials
36
6
With autosamplers, we need to be extra careful to avoid contamination.
Profiling Nonionic Surfactants Applied in Pharmaceutical Formulations by Using Comprehensive Two-Dimensional LC with ELSD and MS Detection
June 01, 2018
Peer-Reviewed
36
6
Comprehensive 2D-LC using HILIC and reversed-phase LC is a robust tool to characterize nonionic ethoxylated surfactants in pharmaceutical formulations.
Chromatography Fundamentals, Part II: Thermodynamics of Liquid Chromatography: Energetics
June 01, 2018
Peer-Reviewed
36
6
We examine the connection between the distribution coefficient and Gibbs free energy, and contributions from enthalpy and entropy.
Biomimetic Chromatography to Accelerate Drug Discovery: Part I
June 01, 2018
Peer-Reviewed
36
6
Drug discovery can be accelerated by chromatographic profiling of analogs by measuring their nonspecific binding to proteins and lipids.