A new approach for the analysis of water in solid pharmaceutical products using headspace gas chromatography (HSGC) with an ionic liquid (IL)-based open tubular capillary GC column has been proposed by scientists at the University of Texas at Arlington (Texas, USA). Published in the Journal of Pharmaceutical and Biomedical Analysis, the study states that the sensitivity of the method is 100 times that of the commonly used volumetric Karl Fischer Titration (KFT) (1).
A novel approach is described for the quantitation of three additives typically used in copper plating using a dual LC system with an ECD and a CAD.
This article addresses the contribution of thermal stability and column activity to BDE-209 breakdown and also describes an optimized method that resolves BDE-209 and other important congeners.
Incognito was met with initial disappointment after attending the Pittcon technical sessions, but was rescued from his gloom by the range of poster presentations on show that stimulated discussion and gave him some new insights (and new hope!) into developments in the field.
The 38th International Symposium on Capillary Chromatography (ISCC) and 11th GCXGC Symposium will be held at the Palazzo dei Congressi in Riva del Garda, Italy, from 18–23 May 2014.
Click the title above to open The Column April 28, 2014 North American issue, Volume 10, Number 7, in an interactive PDF format.
Click the title above to open The Column April 28, 2014 Europe & Asia issue, Volume 10, Number 7, in an interactive PDF format.
Agilent Technologies (California, USA) has announced that Joshua Rabinowitz, a professor at Princeton University (New Jersey, USA), has received an Agilent Thought Leader Award to support his work on quantitative analysis of cellular metabolism.
The latest newsletter from April 24.
The 2015 budget for the US Food and Drug Administration (FDA) will rise by 8.1% over the 2014 budget.
The European Food Safety Authority (EFSA) has put out a call to scientists to join its teams of risk assessment experts and make a difference to Europe?s food safety system.
This blog attempts to provide an impartial guide to liner selection which is representative of the considerations in modern capillary GC.
Click here to view the complete E-Separation Solutions newsletter from April 17, 2014.
The Analytical Division Separation Science Group of the Royal Society of Chemistry has awarded the Knox medal to Peter Schoenmakers of the Van?t Hoff Institute in Amsterdam, the Netherlands.
LCGC recently spoke with the 2014 LCGC Lifetime Achievement Award winner, Fred E. Regnier, the John H. Law Distinguished Professor in the Department of Chemistry at Purdue University in West Lafayette, Indiana, about his early work, his numerous patents and start-up companies, as well as his vast accomplishments in separation science and his role as a teacher.
The latest newsletter from April 17.
In this new short interview, Deirdre Cabooter of KU Leuven in Belgium, discusses the advantages of using UHPLC in method development and tips to follow when transferring methods from UHPLC to HPLC instrumentation.
The aim of this study was to apply quality-by-design principles to build in a more scientific and risk-based multifactorial strategy in the development of an ultrahigh-pressure liquid chromatography (UHPLC) method for omeprazole and its related impurities.
LCGC spoke to Giorgia Purcaro of the Department of Food Science at the University of Udine, Italy, and Chiara Cordero of the Department of Drug Science and Technology at the University of Turin, Italy, about the sensory evaluation of olive oil and the benefits of a comprehensive approach.
Click here to view the complete E-Separation Solutions newsletter from April 10, 2014.
The Working Group Separation Sciences of the Analytical Division of the German Chemical Society has awarded the Eberhard Gerstel Prize to Jakob Haun, a doctoral student at the Institute for Energy and Environmental Technology (Duisburg, Germany) for an outstanding research publication.
The 38th International Symposium on Capillary Chromatography (ISCC) will be held at the Palazzo dei Congressi, in Riva del Garda, Italy, from 18?23 May 2014. The four-day event will feature recent findings from leading academic and industrial experts in the form of lectures and posters. LCGC Europe will be present as Platinum Sponsor during the entire event and welcome you to join us at our booth located in the Exhibition Hall to discuss past, present, and future mutual relationships.
Graduate students seeking doctoral degrees in chemistry require guidance and help in completing their dissertations. In the April installment of The LCGC Blog, Kevin Schug discusses this process and the efforts of four of his students.
The latest newsletter from April 10.
AOAC International (Gaithersburg, Maryland) has named Guo-Fang Pang as the recipient of the 2014 Harvey W. Wiley Award in recognition of his outstanding contributions to analytical chemistry.
AOAC International (Gaithersburg, Maryland) has named Guo-Fang Pang as the recipient of the 2014 Harvey W. Wiley Award in recognition of his outstanding contributions to analytical chemistry.
Four new ozone-depleting substances (ODSs) - CFC–1121, CFC–112a, CFC–113a, and HCF–133a - have been detected and identified in the Earth's atmosphere using gas chromatography–mass spectrometry (GC–MS).1 The research published in Nature Geoscience compared samples collected between 1978 and 2012 to establish a clear increase in the emissions of these gases, even though CFC production has been banned globally since 1987.
Scientists from Bristol-Myers Squibb Company have developed a novel approach for the simultaneous quantitation of neutralizing antibodies, residual drug, and human Immunoglobulin G (IgG) in immunogenicity assay development using liquid chromatography–tandem mass spectrometry (LC–MS–MS). This work published in Analytical Chemistry presents a new approach that aids the refinement of therapeutic protein neutralizing antibody assays in drug development
A team of scientists based in the US has used solid–phase microextraction (SPME) and gas chromatography–mass spectrometry (GC–MS) to provide the first analysis of volatile organic compounds (VOCs) present in human earwax (cerumen).1
There are many sources of advice on how to select the most appropriate stationary phase for sample analysis, but the mobile phase is not often discussed. This article provides tips for selecting the most appropriate mobile phase for your analysis.