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A review of chiral separations, which remain a decided area of interest, particularly in the pharmaceutical and agrochemical fields.

Ron Majors presents a brief introduction to the articles presented in this supplement.

Size-exclusion chromatography is an important technique in biopharmaceutical characterization. This article discusses its use for soluble aggregation analysis and quantitation.

Chromatography has taken a prominent place in the characterization and analysis of protein therapeutic drugs and today it plays a critical role in the biotechnology laboratory.

Controlling particle size distribution is examined as a possible route to further improve the performance of particle-based columns.

An examination of the development of new types of columns based on different particle types, sizes, and other physical characteristics and how they can improve the speed and efficiency of HPLC used to support more expansive and complicated analyses.

Click the title above to open the LCGC Europe 2014 Recent Developments in LC Column Technology Supplement, Vol 27 No s11, in an interactive PDF format.

The pyrolysis–GC–MS method enables direct analysis of solid or liquid polymers without sample pretreatment, as illustrated here for various materials, including a dental filling material and a car wrapping foil.

How large an injection can you make if the injection solvent is not matched to the mobile phase?

An explanation of why HPLC eluent systems are designed as they are.

Here, we examine the various way that chromatographers and chromatography data-handling systems locate and measure peaks.

This month's "GC Connections" examines the various ways - and their attendant benefits and drawbacks - that chromatographers and chromatography data-handling systems locate and measure peaks.

An explanation of why HPLC eluent systems are designed as they are.

How large an injection can you make if the injection solvent is not matched to the mobile phase?

To obtain the best performance from your UHPLC system, you need the right tubing and fittings. Here is what you need to know.

Click the title above to open the LCGC Asia Pacific November 2014 regular issue, Vol 17, No 4, in an interactive PDF format.

Click the title above to open the LCGC Europe November 2014 regular issue, Vol 27, No 11, in an interactive PDF format.

Click the title above to open the LCGC North America November 2014 regular issue, Vol 32 No 11, in an interactive PDF format.

LCGC, the leading resource for separation scientists, is proud to announce that Joseph Jack Kirkland and Caroline West are the winners of the eighth annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively.

In water samples, OCPs are monitored by the U.S. Environmental Protection Agency by various methods including methods EPA 508, EPA 608, and EPA 8081. The use of solid phase extraction (SPE) can rapidly increase both extraction efficiency and reduce lab solvent usage. By implementing the FMS TurboTrace® ABN system with its dual cartridge functionality, an in-line Florisil cartridge can be added to perform automated extract clean-up during the elution step.

This article is an overview of the different types of antibody-drug conjugates (ADC) characterization that can be performed with the light scattering toolkit to support the development of biotherapeutics.

Robin MacGeachy, the Managing Director of Peak Scientific in Inchinnan, Scotland, has been awarded the Ernst and Young UK Entrepreneur of the Year Award for Manufacturing 2014.

A study published in the journal Analytical Chemistry presents the application of a foodomics approach – combining transciptomics with metabolomics – to determine the anticancer mechanism of action of polyphenols contained in Rosmarinus officinalis L., commonly known as rosemary.1

A new study to be published in the journal Food Chemistry proposes 10 compounds that could be used to determine the authenticity of handmade sea salt opposed to industrial sea salt.

How to spot problems in your method before they become an issue.

Incognito ponders if fashion is clouding our judgement when it comes to certain tried and tested techniques.