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If you do Gas Chromatography, then you will have undoubtedly conditioned a capillary GC column ready for use after a period of storage or before first use.

I have had enough conversations with experts in the field of high performance liquid chromatography (HPLC) stationary-phase supports to know that there is more to the increased efficiency provided by the use of superficially porous particles (SPP) compared to fully porous particles (FPP) than simply mass transfer effects. Yet, I would argue that this is still one of the biggest misconceptions propagated by some members of the chromatography community.

A review of the 8th International Symposium on Packed Column SFC (SFC 2014), which was held in Basel, Switzerland, on 8–10 October 2014.

LCGC Blogger Tony Taylor asks if we are too scared to properly explore selectivity options in high performance liquid chromatography (HPLC).

Analysis of paralytic shellfish toxins according to the official AOAC Method 2011.02 using a HPLC single step-gradient method with products of post-column derivatization detected using a fluorescence detector.

Analysis of paralytic shellfish toxins according to the official AOAC Method 2011.02 using a HPLC single step-gradient method with products of post-column derivatization detected using a fluorescence detector.

Immunoaffinity column sample clean-up and HPLC post-column photochemical derivatization with fluorescence detection to analyze sflatoxins B1,B2, G1, and G2.

Immunoaffinity column sample clean-up and HPLC post-column derivatization method to analyze aflatoxins B1, B2, G1, G2 and Ochratoxin A.

Immunoaffinity column sample clean-up and HPLC post-column photochemical derivatization with fluorescence detection to analyze sflatoxins B1,B2, G1, and G2.

Spring Scream is one of the largest music festivals held in Taiwan, and is reported to be associated with drug abuse and addiction.

A new study published in the Journal of Chromatography A presents a sensitive method for the quantification of apidaecins, a type of antimicrobial peptide that play an important role the immune response of honey bees to pathogens. The method was developed using reversed-phase nanoliquid chromatography coupled with high resolution mass spectrometry (LC–MS) to determine apidaecins in hemolymph or body parts from individual honey bees.

Click the title above to open The Column January 08, 2015 Europe & Asia issue, Volume 11, Number 1, in an interactive PDF format.

Click the title above to open The Column January 08, 2015 North American issue, Volume 11, Number 1, in an interactive PDF format.

Incognito discusses how investigating negative data can lead you to an unexpected positive result.

SFC was evaluated as an alternative to HPLC for the enantiomeric separation of primary amines on a cyclofructan-based CSP.

The development of sample prep, separation, and detection methods for the analysis of food and pharmaceutical samples are described.

A snapshot of what’s on offer for chromatographers at Pittcon 2015.

Have a problem with your LC? Maybe applying a little DDT may help.

The fundamentals and applications of pyrolysis-G

Various analytical approaches and instrumentation for low?molecular-weight (MW), noncovalent, aggregates of proteins are discussed.

ISCC and GCXGC 2015

A guide to HPLC detector selection.

The use of a mass spectrometer in quantitative analysis exploits its exquisite selectivity and sensitivity as a detector, allowing a signal to be ascribed to a particular chemical entity with high certainty, even when present in a sample at a low concentration.

On October 21, 2014, University of Tennessee Distinguished Scientist Georges Andre Guiochon succumbed to neuromuscular failure caused by post-polio syndrome. Here, we pay tribute to his remarkable career and life.