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Redox reactions are integral parts of many cellular processes. They are therefore extensively studied in vitro and in vivo. Electrochemistry (EC) represents a purely instrumental approach to characterize direct and indirect effects of redox reactions on bioorganic molecules. This review highlights important trends and recent developments.

This instalment examines ovens for GC in several forms plus how oven thermals affect peak retention behaviour.

A stepwise process is described to help isolate and identify the cause of a method failure.

Event: 21st International Symposium on Separation Sceinces (21st ISSS 2015)

A guide to selecting the correct HPLC stationary phase.

Antec introduced the ROXY as an electrochemical reactor up-front MS. The electrochemically-assisted reduction of disulphide bonds followed by on-line mass spectrometric (MS) detection is presented.

Accurate steroid measurement is essential for the diagnosis of various disorders, for example in sexual differentiation or gonadal function.

Pain management LC analyses can be difficult to optimize because of the limited selectivity of C18 and phenyl-hexyl phases.

Supercritical fluid chromatography (SFC) has been used by scientists in laboratories and manufacturing facilities for several decades.

The physical properties and behaviour of polymers depends strongly on the properties of the polymer molecules themselves

There has been a significant resurgence in the development of antibody-drug conjugates (ADC) as target-directed therapeutic agents for cancer treatment.

Click the title above to open the LCGC Asia Pacific March 2015 regular issue, Vol 18, No 1, in an interactive PDF format.

Click the title above to open the LCGC Europe March 2015 regular issue, Vol 28, No 3, in an interactive PDF format.

Click the title above to open the LCGC North America March 2015 regular issue, Vol 33 No 3, in an interactive PDF format.

Click the title above to open the March 2015 issue of Current Trends in Mass Spectrometry, Volume 13, Number 1, in an interactive PDF format.

Incognito challenges commonly held views about consultants. Are you missing out on their valuable insight and know-how?

Detecting estrogens at trace concentrations in biological fluids is key to understanding their role in the induction - and treatment - of disease. Researchers from the University of Texas Arlington, USA, have developed a method using restricted access-media (RAM) that enables the detection of trace levels of estrogen's using LC–MS–MS without liquid–liquid extraction (LLE) or solid-phase extraction (SPE).

Click the title above to open The Column February 19, 2015 Europe & Asia issue, Volume 11, Number 3, in an interactive PDF format.

Click the title above to open The Column February 19, 2015 North American issue, Volume 11, Number 3, in an interactive PDF format.

Ultra-high performance liquid chromatography (UHPLC) enables fast, efficient separation of biomolec-ular samples. Compared to standard SEC, UHP-SEC provides improved resolution, higher throughput, less solvent and smaller sample consumption for analysis of precious biological samples.

In response to recent accusations levied by the New York State Attorney General’s office that herbal supplements sold by four major retailers contained little or no primary ingredient, the supplements industry is planning further testing of the affected products.

There are often times in my work when I need to 'mess about' with column dimensions and particle morphologies. For 'mess about' read improve or transfer.

Pharmaceutical and personal care products (PPCPs) entering water supplies have been widely studied, but there is little information on the activity of these compounds in swimming pool water. Researchers have applied a PPCP analysis method previously developed for the detection of 32 PPCPs in wastewater to survey indoor swimming pools in the USA.

Mycotoxins are an important group of secondary metabolites produced by fungi that can cause disease in humans and animals. Active in the field of mycotoxin analysis is Rudolf Krska from BOKU, IFA-Tulln in Vienna and in this video he discusses his work investigating the human metabolism of Fusarium mycotoxins and gives his view on the future direction of mycotoxin research.

The lives, careers, and achievements of the 2015 LCGC Award winners - Joseph Jack Kirkland, the winner of the 2015 Lifetime Achievement in Chromatography Award, and Caroline West, the 2015 Emerging Leader in Chromatography - are highlighted here.

I have been at The University of Texas at Arlington for almost 10 years, and I have taught approximately seven different classes in my time here. Yet, the one that I have had the most opportunities to teach, and the most time to reform, is our junior/senior-level Instrumental Analysis (IA) course.